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HIV-1 IN Mutant in a Single Round Vector

Abstract: Antiretroviral therapy (ART) has changed the prognosis of HIV-1 infection to a chronic illness that, in most cases, can be managed or controlled. Integrase strand transfer inhibitors (INSTIs) and reverse transcription inhibitors are essential components of ART drug cocktails. In compliant individuals, ART has been found to block viral replication...

Published: 4/8/2024 | Inventor(s): Steven Smith, Stephen Hughes

Keywords(s): Anti-HIV Drugs, HIV, Hughes, INSTIs, Integrase Strand Transfer Inhibitors, pNL4.3, Reverse Transcriptase, RT, Single-Round Vectors, Smith

Category(s): Application > Research Materials, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing