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Use of Antisense Oligodeoxynucleotides for Inhibiting JC Virus

Progressive multifocal leukoencephalopathy (PML) is a rare, fatal demyelinating disease of the brain caused by the polyomavirus JC (JCV) under immunosuppressive conditions. It is pathologically characterized by progressive damage of white matter of the brain by destroying oligodendrocytes at multiple locations. Clinically, PML symptoms include weakness...

Published: 7/25/2024 | Inventor(s): Avindra Nath, Eugene Major, Maria Monaco-Kushner, Michael Ferenczy, Laura Jaeger

Keywords(s): Anti-JC, Antisense, Cocktail, DAXXXX, DB4BXX, DB4XXX, DB5XXX, DBXXXX, DD1XXX, DDXXXX, DXXXXX, virus, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Infectious Disease