Search Results - antibody+drug+conjugate

2 Results

Sort By:

Development of Next Generation Antibody Drug Conjugates (ADCs) Against CD276

Summary: The National Cancer Institute (NCI) seeks research collaborations and/or licensees for the development of a CD276 antibody drug conjugate (ADC) for the treatment of solid tumors. Description of Technology: Angiogenesis is the formation of new blood vessels from pre-existing blood vessels. Angiogenesis occurs during normal growth and development...

Published: 4/24/2026 | Updated: 8/2/2023 | Inventor(s): Brad St. Croix, Yang Feng, Steven Seaman

Keywords(s): ADC, antibody drug conjugate, B7-H3, CD276, Immunotherapy, Monoclonal Antibody, St. Croix

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics

Her2 Monoclonal Antibodies, Antibody Drug Conjugates as Cancer Therapeutics

Abstract: Antibody drug conjugates (ADC) can demonstrate high efficacy as cancer therapeutics, however, much more can be done to improve their efficacy and safety profile. Site-specific antibody drug conjugation is a promising way to do this. Scientists at the NCI’s Laboratory of Experimental Immunology have identified a fully human monoclonal antibody,...

Published: 4/22/2025 | Updated: 8/2/2023 | Inventor(s): Dimiter Dimitrov, Zhongyu Zhu, Pradman Qasba, Boopathy Ramakrishnan

Keywords(s): ADC, antibody drug conjugate, Dimitrov, HER2, Her2 positive, Her2-overexpression

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology