Search Results - atsushi+kitani

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LRRK2 Inhibitors: Novel Treatment for Intestinal Bowel Disorders

Use of Leucine Rich Repeat Kinase 2 (LRRK2) inhibitors for the treatment of Intestinal Bowel Disorders (IBD) is disclosed. IBD is a broad term that describes conditions with chronic or recurring immune response and inflammation of the gastrointestinal tract. Crohn's disease and ulcerative colitis, two common forms of idiopathic IBD, are chronic, relapsing...

Published: 10/28/2024 | Inventor(s): Tetsuya Takagawa, Atsushi Kitani, Warren Strober

Keywords(s): COLITIS, Crohn's, Disease, IB3XXX, inhibitor, LRRK2, TREAT, Ulcerative, VPXXXX, WKXXXX, XEXXXX, YAXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Endocrinology, TherapeuticArea > Infectious Disease, TherapeuticArea > Dental, TherapeuticArea > Ophthalmology, TherapeuticArea > Immunology, TherapeuticArea > Oncology, TherapeuticArea > Cardiology

Treatment and Prevention of Inflammatory Bowel Disease (IBD) using Mutant and Chimeric IL-13 Molecules

Ulcerative colitis (UC) is a chronic inflammatory disease of the colorectum and affects approximately 400,000 people in the United States. The cause of UC is not known, although an abnormal immunological response to bacterial antigens in the gut microflora is thought to be involved. Present treatments for UC include anti-inflammatory therapy using...

Published: 10/28/2024 | Inventor(s): Warren Strober, Peter Mannon, Jan Preiss, Raj Puri, Koji Kawakami, Stefan Fichtner-Feigl, Atsushi Kitani

Keywords(s): Crohn disease; Inflammatory bowel disease 1, IB3XXX, IB6XXX, IBXXXX, Inflammatory bowel disease 1, IXXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Immunology, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Reproductive Health