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Hybrid Adeno-Retroviral Vector for the Transformation of Cells (E-258-1998)

The invention described and claimed in this patent application provides for novel hybrid vectors which may be used for cell transformation, either in vivo or in vitro. The hybrid vectors have an adenoviral backbone with retroviral long terminal repeats (LTRs). Such vectors are capable of transforming dividing or non-dividing cells and integrate stably...

Published: 7/25/2024 | Inventor(s): Bruce Baum, Brian O'connell, Changyu Zheng

Keywords(s): Adeno-Retroviral, Chimeric Vector, Duke DNA Project, GB2A2X, GB2AXX, GB2XXX, GBXXXX, GENE THERAPY, GXXXXX, hybrid vector, Vector, viral vector

Category(s): Application > Therapeutics