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Use of Neurotrophic Factor-alpha1/Carboxypeptidase E (CPE) to Treat Alzheimer Disease

Summary: The NICHD is seeking licensees for development of Carboxypeptidase E (CPE) as a therapy for MCI or AD. Description of Technology: There is no known cure for Alzheimer’s disease, a brain disorder that severely affects memory, thinking, learning, and organizing skills. It eventually decreases a person’s ability to carry out simple,...

Published: 4/24/2026 | Updated: 8/2/2023 | Inventor(s): Yoke Peng Loh, Yong Cheng

Keywords(s): “Cognitive impairment”, Ad, Alzheimer’s Disease, BNDF, brain, Brain-Derived Neurotrophic Factor, Carboxypeptidase E, CPE, Hippocampus, LOH, MCI, MEMORY, Mild Cognitive Impairment, NEURODEGENERATION, NEUROTROPHIC

Category(s): TherapeuticArea > Neurology, Application > Therapeutics, Collaboration Sought > Licensing, Collaboration Sought > Collaboration