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Efficacious Fluorinated Cytidine Analog Cancer Therapeutic With Low Toxicity In Animal Studies

Abstract: Cytidine analogs remain an area of active drug discovery and development, with five FDA approved drugs for the treatment of acute myeloid leukemia (AML). Two of these drugs, azacitidine (Vidaza®) and decitabine (Dacogen®), which were approved for myelodysplastic syndromes in 2004 and 2006, respectively, inhibit the DNA maintenance...

Published: 4/8/2024 | Inventor(s): Joel Morris, Omar Lopez, Donn Wishka

Keywords(s): colon carcinoma, cytidine analogs, Hodgkin Lymphoma, Morris

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology