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Agonistic Human Monoclonal Antibodies against Death Receptor 4 (DR4)

Abstract: The National Cancer Institute is seeking parties interested in licensing human monoclonal antibodies (mAbs) that bind to death receptor 4 ("DR4"). The tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and its functional receptors, DR4 and DR5, have been recognized as promising targets for cancer treatment. Therapeutics...

Published: 5/22/2024 | Inventor(s): Dimiter Dimitrov, Yang Feng

Keywords(s): ANTIBODY, death receptor, Dr4, Mab, TRAIL

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology