Search Results - filovirus

1 Results

Sort By:

Chimeric SHIV Gag Proteins Optimize T-Cell Response Against HIV Gag

HIV Gag has been included in nearly all HIV vaccines entering clinical trials because of its importance in SIV models and its correlation with protection in HIV-infected long-term non-progressors. However, HIV Gag has proven less immunogenic than Env in phase I clinical trial studies. Through sequence comparison, two regions in HIV Gag have been identified...

Published: 7/25/2024 | Inventor(s): Gary Nabel

Keywords(s): Against, Cell, chimeric, DC5AXX, DC5XXX, DCXXXX, Development, Duke DNA Project, DXXXXX, Filovirus, GAG, HIV, HIV/SIV, Infection, Optimize, PREVENTIVE, primate, proteins, Responses, T, Vaccine, Vaccine-Induced

Category(s): Collaboration Sought > Licensing, Application > Vaccines, TherapeuticArea > Infectious Disease