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Treatment of Periodontal Disease via ENPPI Inhibition

This technology focuses on enhancing cementum production, a key component in treating periodontal regression. The method involves inhibiting ectonucleotide pyrophosphatase phosphodiesterases (ENPP1), enzymes that play a significant role in mineralization processes. Pyrophosphate (PPi) is known to impede the growth of hydroxyapatite crystals, essential...

Published: 8/12/2024 | Inventor(s): Demetrios Braddock, Martha Somerman, Emily Chu, Vivek Thumbigere-Math, Brian Foster, Francisco Nociti

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Category(s): Application > Therapeutics, Collaboration Sought > Licensing, TherapeuticArea > Dental