Search Results - frank+gonzalez

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Non-invasive diagnostic and prognostic assay for early stage lung cancer

Abstract: In the United States alone, one of four cancer deaths occur from lung cancer and there are over 8 million individuals considered to be at high-risk due to cigarette smoking and other behaviors. It's well known that early detection of cancer significantly improves survival of this disease, however a lack of lung cancer screenings and analysis...

Published: 4/8/2024 | Inventor(s): Curtis Harris, Ewy Mathe, Frank Gonzalez, Kristopher Krausz, Soumen Manna, Andrew Patterson, Majda Haznadar

Keywords(s): LDCT, LD-CT, liquid biopsy, low-dose computed tomography, Non-small cell lung cancer, NSCLC, Urine

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Application > Diagnostics, Collaboration Sought > Licensing

Development and Characterization of the SLC46A3 Knockout Mouse Line

Abstract: Nonalcoholic fatty liver disease is caused by several factors including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), an environmental contaminant. TCDD causes lipid accumulation in humans by inducing the Solute Carrier Family 46 Member 3 (SLC46A3) gene expression. To effectively study TCDD-mediated lipid accumulation, research tools such as...

Published: 4/8/2024 | Inventor(s): Frank Gonzalez, Sun Hee Yim, Jung-Hwan Kim

Keywords(s): 2, 3, 7, 8-tetracholodibenzo-p-dioxin, Gonzalez, hepatocellular carcinoma, Knockout Mouse, Liver cancer, Major Facilitator Superfamily, MFS, Nonalcoholic fatty liver disease, OBESITY, SLC46A3, Solute Carrier Family, TCDD

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Endocrinology