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Chromatin Insulator Protecting Expressed Genes of Interest for Human Gene Therapy or Other Mammalian Transgenic Systems

The technology provides the isolation of a functional DNA sequence comprising a chromatin insulating element from a vertebrate system and provides the first employment of the pure insulator element as a functional insulator in mammalian cells. The technology further relates to a method for insulating the expression of a gene from the activity of cis-acting...

Published: 7/25/2024 | Inventor(s): Jay Chung, Gary Felsenfeld

Keywords(s): CB2XXX, CBXXXX, CXXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics