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Combination of recombinant IL-7 with Chimeric Antigen Receptor (CAR) T Cells Targeting Glypican-3 (GPC3) for the Treatment of Hepatocellular Carcinoma (HCC)

Abstract: Hepatocellular carcinoma (HCC) is the most common type of liver cancer. standard treatment for HCC is not suitable for a large proportion of liver cancer patients. As a result, alternative treatments are needed. Chimeric antigen receptor (CAR) T cell therapy is a promising alternative approach selectively targets targeting tumors via tumor-specific...

Published: 5/21/2024 | Inventor(s): Mitchell Ho, Dan Li, Byung Ha Lee, Sara Ferrando-Martinez

Keywords(s): CAR, Chimeric Antigen Receptor T Cell Therapy, Glypican-3, GPC-3, HCC, hepatocellular carcinoma, HO, Interleukin-7, liver, Recombinant IL-7, Tumor Specific Antigen

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Immunology, Application > Therapeutics