Search Results - interferon+gamma

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A Murine Model of Inflammation Based on Chronic Expression of Interferon-Gamma

Abstract: An autoimmune disease is characterized by a malfunctioning healthy immune system mistakenly attacking healthy cells, tissues, and organs. These chronic diseases likely result from interactions between genetic and environmental factors. Gender, race, and ethnicity characteristics have been linked to the development of an autoimmune disease....

Published: 4/8/2024 | Inventor(s): Howard Young, Deborah Hodge

Keywords(s): Autoimmune, Autoinflammatory, IFNγ, immunomodulatory, immunostimulatory, Interferon gamma, Ovarian Failure Syndrome, Primary Biliary Cholangitis, Systemic lupus erythematosus, Young

Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Infectious Disease, TherapeuticArea > Immunology

Peptide Inhibitors for Viral Infections and as Anti-inflammatory Agents

Abstract: IFN-gamma and IL-10 are cytokine signaling molecules that play fundamental roles in inflammation, cancer growth and autoimmune diseases. Unfortunately, there are no specific inhibitors of IFN-gamma or IL-10 on the market to date. NCI investigators at the Cancer and Inflammation Program have synthesized short peptides that selectively interfere...

Published: 4/8/2024 | Inventor(s): Nadya Tarasova, Giorgio Trinchieri, Howard Young, C. Andrew Stewart, Marco Cardone, Alan Perantoni

Keywords(s): IFN-gamma, Interferon gamma, INTERLEUKIN, Peptide, Peptidometic, psoriasis, Synthetic Peptide Inhibitors

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Dermatology, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, TherapeuticArea > Immunology