Search Results - keji+zhao

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Bivalent Tn5 Complex and its Application to Map Enhancer-Promoter Interactions for Use in Diagnostics

This technology includes a new reagent, termed bivalent Tn5 complex, and applied it to mapping genome-wide enhancer-promoter interactions to be utilized for disease diagnostics. Chromatin structure is critical for regulating transcription in normal development and disease states. In particular, the interaction between enhancers and promotes are essential...

Published: 8/12/2024 | Inventor(s): Keji Zhao, Qingsong Tang

Keywords(s):

Category(s): Application > Diagnostics, Collaboration Sought > Licensing, ResearchProducts > Research Equipment

Identification of a Novel Parvovirus for Vaccine Development and Use as a Diagnostic Tool

This technology includes a procedure for novel virus identification in a variety of human specimens by solexa high-throughput sequencing, which allows for the screening a large number of clinical specimens for novel virus discovery in a highly efficient and relatively economical method. By using this technique, we have successfully identified a novel...

Published: 9/5/2024 | Inventor(s): Ning Zhi, Neal Young, Baoyan Xu, Keji Zhao, Gangqing Hu

Keywords(s):

Category(s): Application > Diagnostics, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease

Single cell profiling of chromatin Occupancy and RNAs Sequencing (scPCOR-seq)

Cell-to-cell heterogeneity in gene expression is a widespread phenomenon, and may play important roles in cellular differentiation, function and disease development. Human Cell Atlas aims to profile gene expression in every single human cells. Recent studies have implicated a potential role of chromatin in the heterogeneity in gene expression. Understanding...

Published: 8/12/2024 | Inventor(s): Keji Zhao

Keywords(s):

Category(s): Application > Research Materials, Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Oncology

Genome Wide DNase I Hypersensitive Sites Detection in Formalin-Fixed Paraffin-Embedded Single Cells

A method of detecting DNase I hypersensitive sites ((DHS) in a single cell or very small number of cells, including cells recovered from formalin-fixed paraffin-embedded (FFPE) tissue slides of patient samples. DHS has revealed a large number of potential regulatory elements for transcriptional regulation in various cell types. The application of...

Published: 4/8/2024 | Inventor(s): Qingsong Tang, Keji Zhao

Keywords(s): amplification, AMPLIFICATION-BASED, assay, CHROMATIN, DNase-Seq, Listed LPM Contreras as of 4/15/2015, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Single-cell, TECHNIQUE, VCXXXX, WBXXXX, WIXXXX, XGXXXX, XHXXXX, YAXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Consumer Products, Application > Therapeutics, TherapeuticArea > Oncology, ResearchProducts > Research Equipment, Application > Diagnostics, Application > Research Materials