Search Results - lung+surfactant+homeostasis

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Knockout and Conditional Knockout Mice-GPR116

Abstract: Pulmonary surfactant plays a critical role in preventing alveolar collapse by decreasing surface tension at the alveolar air-liquid interface. Surfactant deficiency contributes to the pathogenesis of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), common disorders that can afflict patients of all ages and carry a mortality...

Published: 7/25/2024 | Inventor(s): Brad St. Croix, Mi Young Yang

Keywords(s): acute lung injury, Acute respiratory distress syndrome, GPR116, lung surfactant homeostasis, mouse model

Category(s): Application > Research Materials, TherapeuticArea > Oncology, Collaboration Sought > Licensing