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Potassium Hydroxy Citrate Promotes Longevity and Efficacy of Anti-Tumor T cells for Adoptive Cell Therapy (ACT)

Abstract: Adoptive cell therapy (ACT) using tumor-specific T cells can produce positive clinical responses in some cancer patients. Nevertheless, several obstacles to the successful use of ACT for the treatment of cancer and other conditions remain. For example, one or more of the in vivo persistence, survival, and antitumor activity of tumor-specific...

Published: 4/8/2024 | Inventor(s): Suman Vodnala, Nicholas Restifo, Rigel Kishton, Robert Eil

Keywords(s): act, adoptive cell therapy, Memory T Cells, Potassium Hydroxy Citrate, Restifo, Vodnala

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Collaboration Sought > Licensing