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Analogues of Modafinil for treating sleep and attention disorders

Abstract: Modafinil has attracted attention for the treatment of cognitive dysfunction in disorders such as attention-deficit/hyperactivity disorder (ADHD) as well as cocaine and methamphetamine dependence. However, modafinil has relatively low affinity for binding to the dopamine transporter (DAT) to block dopamine reuptake, and is water-insoluble,...

Published: 4/8/2024 | Inventor(s): Amy Newman, Oluyomi Okunola-Bakare, Jianjing Cao

Keywords(s): attention deficit/hyperactivity disorder (ADHD), dopamine (DAT), Modafinil, Narcolepsy, norepinephrine (NET), serotonin (SERT)

Category(s): Application > Therapeutics, Collaboration Sought > Licensing