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Abstract: Immortalization of plasma cells leads to Multiple Myeloma (MM). Signaling Lymphocyte Activation Molecule F7 (SLAMF7) is highly expressed on the malignant plasma cells that constitute Multiple Myeloma. The expression of SLAMF7 by MM cells and lack of expression on nonhematologic cells makes SLAMF7 a promising target for chimeric antigen receptor...

Published: 5/21/2024 | Inventor(s): James Kochenderfer, Steven Feldman

Keywords(s): act, adoptive cell therapy, CAR, chimeric antigen receptor, Kochenderfer, Multiple Myeloma MM, SLAMF7

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology