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Phantasmidine, a Nicotinic Receptor Agonist for the Treatment of Addiction and Neurological Disorders

The inventors have isolated and characterized an alkaloid, phantasmidine, from the skin of the Ecuadoran poison frog E. anthonyi. Phantasmidine is selective for beta4-containing receptor subtypes, unlike many nicotinic receptor agonists currently in development, which target beta2-containing receptor subtypes. This selectivity makes phantasmidine...

Published: 7/25/2024 | Inventor(s): Richard Fitch

Keywords(s): ADDICTION, AGONIST, Alkaloid, Alzheimer disease 1, Alzheimer disease 3, Alzheimer disease 4, Alzheimer disease type 1, Alzheimer disease type 4, Alzheimer disease, familial, type 3, EPIBATIDINE, IBXXXX, IXXXXX, nAChR, NBXXXX, NC2XXX, NCXXXX, Neurological, neurological disease, nicotine, NICOTINIC, NXXXXX, Patent Category - Chemistry, Phantasmidine

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Neurology, Application > Research Materials, Application > Diagnostics