Search Results - nctt

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The NCGC BioPlanet: A Computational Algorithm to Display Networks in Three Dimensions

This technology includes a novel computational algorithm and software implementation to map and display biological pathways and their relationship on the surface of a globe in a three-dimensional space. Currently, biological pathways and genes are represented as two-dimensional networks, which is not effective for displaying complicated relationships...

Published: 10/28/2024 | Inventor(s): Yuhong Wang, Christopher Austin, Ruili Huang

Keywords(s): Biological, BioPlanet:, Globe, NCGC, NCTT, PATHWAY, VPXXXX, WIXXXX, WMXXXX, XBXXXX, XHXXXX, XJXXXX

Category(s): TherapeuticArea > Ophthalmology, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, ResearchProducts > Computational models/software, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, Application > Software / Apps, Application > Research Materials, ResearchProducts > Research Equipment

Methods of Treating Giardiasis Using FDA-Approved Compounds

This technology includes a group of at least twenty-nine, diverse, commercially available compounds that are newly identified for activity against Giardia lamblia parasites. At least six of the candidate compounds, Bortezomib, Decitabine, Hydroxocobalamin, Amlexanox, Idarubicin, and Auranofin have preexisting FDA approval for human use for other (non-Giardia)...

Published: 10/28/2024 | Inventor(s): Catherine Chen, Juan Marugan, Noel Southall, Christopher Austin, Osnat Herzberg, Andrey Galkin, Wei Zheng

Keywords(s): compounds, DB2XXX, DBXXXX, DXXXXX, Giardiasis, NCTT, Novel, treatment

Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Infectious Disease

Novel Small Molecule Inhibitors for the Treatment of Huntington’s Disease

This technology is a collection of small molecules screened for their ability to prevent or reduce the cytotoxic effects of the protein, Huntingtin. Huntington's disease is a neurodegenerative disorder due to a dominantly acting expansion of a CAG trinucleotide repeat in exon 1 of the Huntington (HTT) gene resulting in production of the altered (mutant)...

Published: 10/28/2024 | Inventor(s): Joshua McCoy, Samarjit Patnaik, Steven Titus, Wei Zheng, Noel Southall, Wenwei Huang, Juan Marugan

Keywords(s): ANALOGUES, Disease, HUNTINGTON'S, IB6XXX, IBXXXX, IXXXXX, NCTT, Novel, Thio-ether, treatment

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Reproductive Health, Application > Research Materials, Application > Diagnostics