Search Results - nelson+ellmore

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Parental A2780 Ovarian Cancer Cell Line and Derivative Cisplatin-resistant and Adriamycin-resistant A2780 Cell Lines

Abstract: Ovarian cancer is one of the most common and lethal types of gynecological malignancies worldwide, accounting for approximately 295,000 new cases and 185,000 deaths annually. The high lethality rate is due to multiple reasons, including recurrence and the resistance of recurrent tumors to chemotherapy. Cell line models are crucial for preclinical...

Published: 4/8/2024 | Inventor(s): Stuart Aaronson, Nelson Ellmore

Keywords(s): A2780, Aaronson, adriamycin, CISPLATIN, drug resistance, IRRADIATION, Melphalan, OVARIAN CANCER, VINBLASTINE

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Research Materials

Human Synovial Sarcoma Cell Line A2243

Abstract: Synovial sarcoma is a cancer affecting mesenchymal cells in connective tissues. This rare cancer is typically linked to genetic abnormalities or exposure to radiation. Metastatic growth throughout the body can occur primarily through blood circulation. More than 90% of synovial sarcomas show a characteristic t(X;18)(p11;q11) translocation...

Published: 7/25/2024 | Inventor(s): Stuart Aaronson, Nelson Ellmore

Keywords(s): A2243, Aaronson, Chromosomal Translocation, CONNECTIVE TISSUE, Drug Screening, Human Cell Line, Mesenchymal Cells, Rare Cancer, SSX, Synovial sarcoma, SYT, tumor formation

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Research Materials