Search Results - niraj+tolia

2 Results

Sort By:

Novel malaria vaccine candidates comprising engineered nanoparticles

Using proteins derived from the malaria Plasmodium falciparum parasite, NIAID has developed three different nanoparticle platforms to serve as scaffolds for displaying multiple copies of malaria antigens in an organized, repetitive manner to enhance vaccine effectiveness. The first platform uses the pyridoxal 5’-phosphate (PLP) synthase protein...

Published: 3/23/2026 | Updated: 3/23/2026 | Inventor(s): Niraj Tolia, Dashuang Shi, Vu Nguyen, Thayne Dickey

Keywords(s):

Category(s): TherapeuticArea, ResearchProducts, Collaboration Sought, Application > Vaccines

Novel VAR2CSA Immunogens and Methods of Use Thereof

The invention provides immunogen polypeptides comprising fragments of VAR2CSA protein expressed by P. falciparum as potential second-generation placental malaria vaccine candidates. VAR2CSA is the leading antigen target for a placental malaria vaccine, where associated antibody titers are correlated with protection. Aspects of the inventive immunogen...

Published: 4/18/2025 | Updated: 12/6/2022 | Inventor(s): Rui Ma, Niraj Tolia

Keywords(s): Against, CANCER, COMPOSITION, COMPRISING, Diagnostics, IMMUNOGENS, Malaria, Matter, Placental, PROTECT, proteins, That, therapeutics, Used

Category(s): Collaboration Sought > Collaboration