Search Results - orit+jacobson+weiss

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Radiotherapy and Imaging Agent-based on Peptide Conjugated to Novel Evans Blue Derivatives with Long Half-life and High Accumulation in Target Tissue

This technology includes a newly designed, truncated Evans Blue (EB) form which allows labeling with metal isotopes for nuclear imaging and radiotherapy. Unlike previous designs, this new form of truncated EB confers site specific mono-labeling of desired molecules. The newly designed truncated EB form can be conjugated to various molecules including...

Published: 8/12/2024 | Inventor(s): Xiaoyuan (Shawn) Chen, Orit Jacobson weiss

Keywords(s):

Category(s): ResearchProducts > Research Equipment, TherapeuticArea > Oncology, Application > Diagnostics, Application > Research Materials

Evans Blue Modified Small Molecule-based Prostate-specific Membrane Antigen (PSMA) Radiotherapy and Nuclear Imaging

This technology includes anti-PSMA antibody labeled with 177Lu, which has shown to be an effective treatment for prostate cancer. Several small molecules targeting PSMA were also evaluated in prostate cancer patients labeled with betta emitters such as 177Lu. The most common one is 177Lu-PSMA-617 which is under clinical evaluation in many countries....

Published: 8/12/2024 | Inventor(s): Xiaoyuan (Shawn) Chen, Orit Jacobson weiss

Keywords(s):

Category(s): Application > Therapeutics, Collaboration Sought > Licensing, ResearchProducts > Antibodies, TherapeuticArea > Oncology