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Zip14-AAV Genetic MRI Reporter System for Non-Invasive Cell & Gene-Therapy Tracking

This technology includes a gene-based magnetic resonance imaging (MRI) reporter platform that harnesses adeno-associated virus (AAV) delivery of the metal transporter Zip14 to create image contrast wherever the gene is expressed. By driving Zip14 from cell-specific promoters, investigators obtain robust, long-lasting signal changes on standard clinical...

Published: 6/18/2025 | Inventor(s): Harikrishna (Hari) Rallapalli, Alan Koretsky, Raymond (Ray) Fields

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Category(s): Application > Diagnostics, Application > Therapeutics, TherapeuticArea > Neurology, TherapeuticArea > Radiology, Collaboration Sought > Licensing