Search Results - alan+koretsky

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High Relaxivity Mulitivalent Gadolinium on a Peptide Scaffold for Targeted MRI Applications in Disease Diagnosis

This technology includes a peptide containing alternating Alanine and Lys(DOTA-Gd) residues can be used to increase the MRI relaxivity of a peptide. The low molecular weight construct can be appended to proteins, antibodies and peptides to increase MRI signals. This approach offers advantages over previous dendrimeric constructs. The increased MRI signal...

Published: 8/12/2024 | Inventor(s): Rolf Swenson, Alan Koretsky, Nikorn Pothayee, Deepak Sail

Keywords(s):

Category(s): Application > Diagnostics, Application > Medical Devices, Application > Research Materials, Collaboration Sought > Licensing

A Current Amplifier for Local Coil Pre-amplification of NMR/MRI Signals

The magnetic resonance imaging (MRI) systems are used for a variety of imaging application. The present invention discloses an improving MRI device and method by amplifying signals received by resonant NMR coils of MRI systems. It utilizes positive feedback from low-noise Field-Effect Transistor to amplify the signal current that can be coupled out...

Published: 7/25/2024 | Inventor(s): Stephen Dodd, Alan Koretsky, Chunqi Qian, Joseph Murphy-Boesch

Keywords(s): AA3AXX, AA3B1X, AC1XXX, AMPLIFIER, Coil, Current, LOCAL, NMR/MRI, OfNMRIMRI, Pre-amplification, SIGNALS, VCXXXX, WBXXXX, WCXXXX, WIXXXX, XDXXXX, XFXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, Application > Research Materials, Application > Diagnostics, Application > Occupational Safety and Health, Application > Non-Medical Devices, Application > Medical Devices, TherapeuticArea > Oncology, Application > Software / Apps

Multilayered RF Coil System for Improving Transmit B1 Field Homogeneity in High-Field MRI

Available for licensing and commercial development is a multilayered radio-frequency (RF) coil system for improving the transmit B1 field homogeneity for magnetic resonance imaging (MRI) at high field strengths. The current invention aims at manipulating the inhomogeneous profile of the transmit B1 field, which causes MR images to become less uniform...

Published: 7/25/2024 | Inventor(s): Shumin Wang, Jozef (Jeff) Duyn, Hellmut Merkle, Alan Koretsky

Keywords(s): AA3AXX, AA3B1X, AA3BXX, AA3XXX, AAXXXX, AXXXXX, Circuitry, IMAGING, Magnetic Resonance, MRI, PASSIVE, Patent Category - Mech/Elect/Soft, RF coil

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Microfabricated Particles Useful as MRI Contrast Agents

MRI contrast agents are versatile yet lack the sensitivity and multiplexing capabilities of optical agents. Available for licensing is an invention pertaining to microfabricated structures that can be used as MRI contrast agents with enhanced functionality or as micro-RFID (radio-frequency identification) tags. The microstructures can be engineered...

Published: 7/19/2024 | Inventor(s): Stephen Dodd, Alan Koretsky, John Moreland, Gary Zabow

Keywords(s): AA1XXX, AA3CXX, AA3XXX, AAXXXX, AB3CXX, AB3XXX, ABXXXX, AXXXXX, IMAGING, imaging agent, ImagingMRI, Magnetic, Magnetic Resonance, Microstructures, MRI, Resonance, STENT, Stents, SYSTEMS

Category(s): Collaboration Sought > Collaboration