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Micropatterning of Extracellular Matrix Proteins Using Microphoto-ablation Of Poly vinyl Alcohol (PVA) Monolayers

Available for licensure and commercial development is a micro-photoablation (µPA) method used as a micro-patterning technique to attach ECM proteins or other biological molecules to specified locations. Advantages of this photolytic technique are that it: (a) is stampless, (b) allows for flexible pattern generation to the submicron level, (c) allows...

Published: 7/25/2024 | Inventor(s): Kenneth Yamada, Andrew Doyle

Keywords(s): AA2XXX, AA3AXX, AA3XXX, AAXXXX, AC3XXX, ACXXXX, AXXXXX, CELL-BINDING, Cellular Interactions, Extracellular, INTERACTION, INTERACTIONS, Micropatterning, Microphoto-ablation, Polyvinyl, PVA

Category(s): Application > Research Materials, ResearchProducts > Research Equipment

A Novel X-ray Grating to Enhance Phase Contrast Imaging

The present invention relates to improving x-ray phase contrast imaging. The invention discloses a novel grating interferometer for phase contrast imaging with hard x-rays that overcomes limitations in the level of sensitivity by utilizing the advantages of far-field interferometers. The novel design and fabrication process can easily acquire absolute...

Published: 7/25/2024 | Inventor(s): Han Wen

Keywords(s): AA3XXX, Balanced, GRATING, INTERFEROMETER, Two-arm, VCXXXX, VDXXXX, WBXXXX, WIXXXX, XDXXXX, XFXXXX, X-RAY, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, Application > Software / Apps, Application > Medical Devices, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Oncology

A Novel Demodulation System in X-ray Imaging

In various x-ray imaging methods, including scattering correction and phase contrast imaging, intensity modulation in space is introduced into the projection images by the use of masks, gratings, or apertures. The present invention relates to a process to demodulate the modulation. The current demodulation processes are either to remove the modulation...

Published: 7/25/2024 | Inventor(s): Houxun Miao, Han Wen

Keywords(s): AA3XXX, Demodulation, IMAGING, INTENSITY, Modulation, VCXXXX, VDXXXX, VEXXXX, VPXXXX, WBXXXX, WIXXXX, XDXXXX, XFXXXX, X-RAY, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Ophthalmology, TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Software / Apps, TherapeuticArea > Neurology, Application > Research Materials, Application > Diagnostics, Application > Medical Devices

Focused Electrostatic Collection of Aerosol Particles for Chemical Analysis by Spectroscopic Techniques

This CDC-developed technology is an aerosol preconcentration unit (APU) designed for use with spectroscopic detection techniques, including emission, Raman, or infrared spectroscopies. Most existing pulsed microplasma techniques, such as laser-induced breakdown, for aerosols rely mainly on filter-based collection and suffer from poor accuracy, precision,...

Published: 7/25/2024 | Inventor(s): Prasson Diwakar, Pramod Kulkarni

Keywords(s): AA2XXX, AA3AXX, AA3B5X, AA3CXX, AA3XXX, AC1XXX, AC3XXX, AC4XXX, AC6XXX, ACXXXX, ADXXXX, AE2AXX, AE2XXX, AE3XXX, AE4XXX, AEROSOL, AEXXXX, AG1XXX, ANALYSER, ANALYSES, analysis, apparatus, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, DAXXXX, DEVICE, DXXXXX, IA5XXX, IDXXXX, Method, NIOSH, NIOSH-DART, OID-NCIRD-DVD, optical, PLASMA, SPECTROSCOPY, TECHNIQUE, VBXXXX, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WEXXXX, WFXXXX, WGXXXX, WIXXXX, WMXXXX, XDXXXX, XFXXXX, XGXXXX, XHXXXX, XIXXXX, YEXXXX, YFXXXX

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Medical Devices, ResearchProducts > Research Equipment, Application > Research Materials, Application > Occupational Safety and Health, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, TherapeuticArea > Ophthalmology, Application > Consumer Products, TherapeuticArea > Oncology, TherapeuticArea > Pulmonology, Application > Non-Medical Devices, TherapeuticArea > Infectious Disease, Application > Software / Apps, TherapeuticArea > Cardiology

Auscultatory Training System and Telemedicine Tool with Accurate Reproduction of Physiological Sounds

This CDC developed auscultatory training apparatus includes a database of prerecorded physiological sounds (e.g., lung, bowel, or heart sounds) stored on a computer for playback. Current teaching tools, which utilize previously recorded sounds, suffer from the disadvantage that playback environments cause considerable distortion and errors in sound...

Published: 7/25/2024 | Inventor(s): Jeffrey Reynolds, Kimberly Friend, William Goldsmith, David Frazer, Walter McKinney

Keywords(s): AA3B6X, AA3BXX, AA3XXX, AAXXXX, AB4XXX, ACXXXX, ADXXXX, AFXXXX, Auscultatory, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, IA1XXX, IA5XXX, IAXXXX, IB1FXX, IB4XXX, ICXXXX, IDXXXX, IXXXXX, NIOSH-HELD, System, TRAINING, VDXXXX, VOXXXX, VPXXXX, WBXXXX, WFXXXX, WHXXXX, WIXXXX, WMXXXX, XDXXXX, XFXXXX, XIXXXX, XJXXXX, YEXXXX, YFXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Endocrinology, Application > Therapeutics, TherapeuticArea > Infectious Disease, TherapeuticArea > Cardiology, ResearchProducts > Computational models/software, Application > Non-Medical Devices, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Ophthalmology, TherapeuticArea > Oncology, Application > Software / Apps, Application > Occupational Safety and Health, Application > Medical Devices, TherapeuticArea > Pulmonology, Application > Research Materials, Application > Diagnostics

Automated Microscopic Image Acquisition, Compositing and Display Software Developed for Applied Microscopy/Cytology Training and Analysis

Micro-Screen is a CDC developed software program designed to capture images and archive and display a compiled image(s) from a portion of a microscope slide in real time. This program allows for the re-creation of larger images that are constructed from individual microscopic fields captured in up to five focal planes and two magnifications. This program...

Published: 7/25/2024 | Inventor(s): Roger Taylor, James Lange, Tommy Lee, Carlyn Collins, MariBeth Gagnon

Keywords(s): AA3AXX, AA3B6X, AA3CXX, AA3XXX, AC2XXX, AC3XXX, Acquisition, ACXXXX, AD2XXX, AD3XXX, ADXXXX, Automated, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositing, DISPLAY, Image, MICROSCOPIC, OID-NCPDCID-DLS, VAXXXX, VBXXXX, VCXXXX, VDXXXX, VEXXXX, VFXXXX, VGXXXX, VHXXXX, VIXXXX, VJXXXX, VKXXXX, VLXXXX, VMXXXX, VNXXXX, VOXXXX, VPXXXX, WBXXXX, WIXXXX, WMXXXX, XDXXXX, XFXXXX, XHXXXX, XJXXXX, YBXXXX, YEXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Psychiatry/Mental Health, Application > Consumer Products, TherapeuticArea > Neurology, TherapeuticArea > Oncology, ResearchProducts > Computational models/software, TherapeuticArea > Cardiology, TherapeuticArea > Dental, Application > Medical Devices, TherapeuticArea > Geriatrics, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Immunology, TherapeuticArea > Ophthalmology, TherapeuticArea > Endocrinology, Application > Non-Medical Devices, TherapeuticArea > Infectious Disease, Application > Software / Apps, Application > Research Materials, ResearchProducts > Research Equipment, Application > Diagnostics

MRI Scanner Bore Covering

This invention pertains to a bore covering for creating controlled environments and specifically for maintaining temperature within the bore of an MRI scanner. The bore covering includes a covering sheet with fastening means (e.g., weak-tack adhesive, pressure-sensitive adhesive or low-tack adhesive) around its inner surfaces that permits reversible...

Published: 7/25/2024 | Inventor(s): Michael Hansen, Robert Lederman, Anthony Faranesh, Kanishka Ratnayaka, Robert Balaban

Keywords(s): AA2XXX, AA3B1X, AA3BXX, AA3XXX, AA4BXX, AA4XXX, AA6XXX, AAXXXX, AE1CXX, AE1XXX, AEXXXX, AXXXXX, BORE, Climate Control, INCUBATOR, MRI, temperature, Temperature-controlled

Category(s): Collaboration Sought > Collaboration

Background-Free Fluorescent Nanodiamond Imaging

Available for licensing and commercial development are intellectual property rights covering a method of imaging a biological specimen (e.g., human tissue) using fluorescent nanodiamonds implanted into the subject of interest, applying a magnetic field to said subject and producing a resultant image by a net juxtaposition of a second acquired image....

Published: 7/25/2024 | Inventor(s): Ambika Bumb, Keir Neuman

Keywords(s): AA3AXX, AA3XXX, AAXXXX, AXXXXX, Background-free, IMAGING, MRI, Nanodiamond

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Magnetic Resonance Arterial Wall Imaging Methods that Compensate for Patient Aperiodic Intrinsic Cardiac, Chest Wall, and Blood Flow-Induced Motions

The technology includes MRI methods, systems, and software for reliably imaging vasculature and vascular wall thickness while compensating for aperiodic intrinsic motion of a patient during respiration. To overcome the loss of the orthogonality due to uncompensated residual motions and after a lapse of time equal to the trigger delay commenced at the...

Published: 7/25/2024 | Inventor(s): Ahmed Gharib, Roderic Pettigrew, Khaled Abd-Elmoniem

Keywords(s): AA3AXX, AA3XXX, AAXXXX, AD3XXX, ADXXXX, Angiographic, ANGIOGRAPHY, ARTERIAL, ARTERIOSCLEROSIS, AXXXXX, Cardiac, CARDIOCIRULATORY, Cardiovascular, MRI, VASCULATURE, Vasculture

Category(s): Collaboration Sought > Collaboration

Fast Acting Molecular Probes for Real-Time In Vivo Study of Disease and Therapeutics

This technology is for fast acting molecular probes made from a fluorescent quencher molecule, a fluorophore, an enzyme cleavable oligopeptide (for example targeted by protease) and FDA-approved polyethylene glycol (PEG) as well as associated methods to identify cell activity with these probes. Proteases regulate many cell processes such as inflammation...

Published: 7/25/2024 | Inventor(s): Seulki Lee, Lei Zhu, Xiaoyuan (Shawn) Chen

Keywords(s): AA3AXX, AA3XXX, AAXXXX, ACTING, Activity, AXXXXX, Beacon, fast, IMAGING, Molecular, PROTEASE, THEREOF, USES

Category(s): Collaboration Sought > Collaboration

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