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Micropatterning of Extracellular Matrix Proteins Using Microphoto-ablation Of Poly vinyl Alcohol (PVA) Monolayers
Available for licensure and commercial development is a micro-photoablation (µPA) method used as a micro-patterning technique to attach ECM proteins or other biological molecules to specified locations. Advantages of this photolytic technique are that it: (a) is stampless, (b) allows for flexible pattern generation to the submicron level, (c) allows...
Published: 7/25/2024   |   Inventor(s): Kenneth Yamada, Andrew Doyle
Keywords(s): AA2XXX, AA3AXX, AA3XXX, AAXXXX, AC3XXX, ACXXXX, AXXXXX, CELL-BINDING, Cellular Interactions, Extracellular, INTERACTION, INTERACTIONS, Micropatterning, Microphoto-ablation, Polyvinyl, PVA
Category(s): Application > Research Materials, ResearchProducts > Research Equipment
Novel Magnetic Resonance Spectroscopy (MRS) Technique to Quantify Brain Metabolites
With respect to quantification of metabolites in the brain, conventional methods of magnetic resonance spectroscopy (MRS) yield results that are highly variable and highly dependent on the sequence type being applied. This invention describes a novel MRS technique that involves preparing longitudinal steady states at different flip angles using trains...
Published: 7/25/2024   |   Inventor(s): Jun Shen, Linqing Li
Keywords(s): AAXXXX, DRIVEN, IMAGING, ImagingMRI, LINEAR, METABOLITE, MRI, NCXXXX, Probing, QUANTIFICATION, Relaxation, RF, States, Steady, VCXXXX, VEXXXX, Vivo, VNXXXX, WBXXXX, XFXXXX, YAXXXX, YDXXXX
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Neurology, TherapeuticArea > Psychiatry/Mental Health, Application > Non-Medical Devices, TherapeuticArea > Oncology, Application > Software / Apps, Application > Medical Devices, Application > Diagnostics, Application > Research Materials
Occupational Safety: Portable Exposure Assessment System for Prevention of Musculoskeletal Injury
CDC researchers have developed the Portable Exposure Assessment System (PEAS), a field-based, remotely deployed tool to monitor and provide early warning of working conditions that have a high likelihood of musculoskeletal injury. PEAS is a noninvasive, real-time, instrument-based system. Sensor technology simultaneously measures and collects data...
Published: 7/25/2024   |   Inventor(s): Bryan Wimer, Shengke Zeng, Christopher Pan
Keywords(s): AA1XXX, AA4XXX, AAXXXX, AE1BXX, AE1CXX, AE1XXX, AE2AXX, AE2BXX, AE2XXX, AE3XXX, AE4XXX, AEXXXX, AFXXXX, AG3XXX, AGXXXX, apparatus, ASSESSING, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Conditions, Injured, Injuries, INJURY, LEAD, Likely, lumbar, Method, MOBILE, MOBILES, MUSCLE, Muscles, MUSCULAR, musculoskeletal, NIOSH, NIOSH-DSR, Occupational health, PERSONAL, Personalized, Portable, SAFE, Safely, SAFETY, System, VMXXXX, VPXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, WMXXXX, WORKER, WORKER safety, WORKERS, XDXXXX, XHXXXX, XIXXXX, XJXXXX, YAXXXX, YEXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, ResearchProducts > Research Equipment, Application > Software / Apps, Application > Medical Devices, Application > Diagnostics, TherapeuticArea > Neurology, Application > Research Materials, TherapeuticArea > Ophthalmology, TherapeuticArea > Cardiology, ResearchProducts > Computational models/software, Application > Non-Medical Devices, Application > Occupational Safety and Health, TherapeuticArea > Endocrinology, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Oncology
Hearing Safety Devices: System for Monitoring Exposure to Impulse Noise
This CDC-developed technology entails a system for monitoring and assessing the risk of auditory damage from exposure to impulse noise, such as noise created by construction machinery and firearms. Noise dosimeters have been used extensively over the past two decades to document personal exposure to noise and assure workplaces comply with permissible...
Published: 7/25/2024   |   Inventor(s): Chucri Kardous
Keywords(s): AA5XXX, AAXXXX, AC1XXX, AC2XXX, ADXXXX, AE1BXX, AE1XXX, AE2BXX, AE2XXX, AE3XXX, AEXXXX, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Exposure, firearm, firearm safety, IMPULSE, MONITORING, NIOSH, NIOSH-DART, NOISE, Occupational health, SAFETY, Sampling, System, VPXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, WMXXXX, XDXXXX, XIXXXX, XJXXXX, YEXXXX
Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, ResearchProducts > Computational models/software, Application > Research Materials, TherapeuticArea > Cardiology, TherapeuticArea > Ophthalmology, TherapeuticArea > Endocrinology, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, Application > Software / Apps, Application > Non-Medical Devices, Application > Medical Devices
Improved Acoustic Plethysmograph System for Noninvasive Measurement of Pulmonary Function
CDC researchers have developed a novel acoustic whole body plethysmograph (AWBP) that allows measurement of tidal volume in lab animals, independent of gas compression in the lung. This system provides particular advantages over the traditional whole body plethysmograph (WBP) when measuring model animals with increased gas compression due to increased...
Published: 7/25/2024   |   Inventor(s): David Frazer, Jeffrey Reynolds
Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC1XXX, AC2XXX, AC3XXX, AC6XXX, Acoustic, ACXXXX, ADXXXX, AE1BXX, AE1XXX, AE3XXX, AE4XXX, AEXXXX, ANIMAL, Animal Model, ANIMAL welfare, ASTHMA, Breath, BREATHING, CDC Docket Import, CDC Docket Import CDC Prosecuting, DDXXXX, DEVICE, DEXXXX, DXXXXX, FUNCTION, IA3XXX, IA5XXX, ICXXXX, IDXXXX, LUNG, lung cancer, Lung Disease, LUNGS, Lung-Targeted, Measuring, NIOSH, NIOSH-HELD, Plethysmograph, Pulmonary, Pulmonary edema, PULMONARY FIBROSIS, research, RESEARCH TOOL, RESPIRABLE, Respiration, respiratory, Respiratory Diseases, respiratory INFECTION, Tool, VBXXXX, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WGXXXX, WIXXXX, WMXXXX, XDXXXX, XHXXXX, XIXXXX, XJXXXX, YCXXXX, YEXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, Application > Software / Apps, Application > Medical Devices, Application > Diagnostics, TherapeuticArea > Pulmonology, TherapeuticArea > Immunology, Application > Research Materials, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Vaccines, Application > Therapeutics, Application > Occupational Safety and Health, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, ResearchProducts > Computational models/software, TherapeuticArea > Oncology
Multiplex Assay for Rapid Salmonella Serotyping from Human, Animal, Food and Environmental Sources
CDC researchers have developed a bead-based nucleic acid assay for serotyping members of the Salmonella genus; this assay will identify serotypes for approximately 95% of all human-obtained Salmonella isolates in the United States. Presently, production and quality control for the more than 250 antisera required to cover the >2,500 known serotypes using...
Published: 7/25/2024   |   Inventor(s): John McQuiston, Collette Fitzgerald Leaumont, Patricia Fields
Keywords(s): AA5XXX, AAXXXX, AFXXXX, assay, Bead, Beads, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, diagnostic, Diagnostic assay, DXXXXX, FOOD, FOOD PATHOGEN, FOOD-ASSOCIATED, Foodborne, ivd, NAT, Nucleic, OID-NCEZID-DFWED, PLATE-BASED, RAPID, SALMONELLA, Serotype, SEROTYPING, VETERINARY, VJXXXX, VOXXXX, WBXXXX, WCXXXX, WFXXXX, WMXXXX, XEXXXX, YBXXXX, Zoonotic
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Diagnostics, Application > Occupational Safety and Health
Mining Safety: Personal Dust Monitor Filters for Accurate, Quantifiable Spectrometric Analysis and Assessment of Worker Exposure Levels
This CDC-developed invention pertains to a novel dust monitor filter that is specially constructed of organic materials for spectrometric analysis, ultimately allowing for detection and accurate quantification of a particular chosen analyte (e.g., crystalline silica/quartz dust that may lead to silicosis). For miners, the risk of lung disease increases...
Published: 7/25/2024   |   Inventor(s): Donald Tuchman
Keywords(s): AAXXXX, AC1XXX, AC3XXX, ACXXXX, AE1XXX, AE2XXX, AE3XXX, AE4XXX, AEXXXX, AIRBORNE, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, CHARACTERIZING, COAL, DUST, Dust collector, Methods, MINE, MINER, MINING, MONITOR, NIOSH, NIOSH-PRL, PARTICULATES, VPXXXX, WBXXXX, WCXXXX, WEXXXX, WFXXXX, WGXXXX, WMXXXX, XDXXXX, XIXXXX, YAXXXX, YBXXXX, YEXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, Application > Non-Medical Devices, Application > Occupational Safety and Health, TherapeuticArea > Ophthalmology, TherapeuticArea > Cardiology, Application > Diagnostics, Application > Consumer Products, TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Medical Devices, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease
Multivalent, Multiple-Antigenic-Peptides for Serological Detection of HIV-1 Groups -M, -N, -O, and HIV-2
This CDC-developed invention pertains to multivalent antigenic peptides (MAPs) that can be used in a variety of HIV/AIDS diagnostics. There are two types of HIV: HIV-1 and HIV-2. HIV-1 is subdivided into groups M, N, and O, while HIV-2 is subdivided into subtypes A and B. Within HIV -1 group M, several different subtypes and numerous forms of recombinant...
Published: 7/25/2024   |   Inventor(s): Chou-Pong Pau
Keywords(s): 0, AAXXXX, AIDS, antibodies, ANTIGEN, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA4AXX, DA4XXX, DAXXXX, Detection, DEVELOPING, DXXXXX, GROUP, HIV-1, HIV-2., LATERAL, M, MAPS, Multiple-antigenic-peptides, MULTIVALENT, N, RESEARCH MATERIAL, virus, VLXXXX, WBXXXX, WFXXXX, WIXXXX, XAXXXX, XCXXXX, XEXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, ResearchProducts > Antibodies, TherapeuticArea > Immunology, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Infectious Disease, Application > Occupational Safety and Health, Application > Therapeutics, Application > Consumer Products
Auscultatory Training System and Telemedicine Tool with Accurate Reproduction of Physiological Sounds
This CDC developed auscultatory training apparatus includes a database of prerecorded physiological sounds (e.g., lung, bowel, or heart sounds) stored on a computer for playback. Current teaching tools, which utilize previously recorded sounds, suffer from the disadvantage that playback environments cause considerable distortion and errors in sound...
Published: 7/25/2024   |   Inventor(s): Jeffrey Reynolds, Kimberly Friend, William Goldsmith, David Frazer, Walter McKinney
Keywords(s): AA3B6X, AA3BXX, AA3XXX, AAXXXX, AB4XXX, ACXXXX, ADXXXX, AFXXXX, Auscultatory, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, IA1XXX, IA5XXX, IAXXXX, IB1FXX, IB4XXX, ICXXXX, IDXXXX, IXXXXX, NIOSH-HELD, System, TRAINING, VDXXXX, VOXXXX, VPXXXX, WBXXXX, WFXXXX, WHXXXX, WIXXXX, WMXXXX, XDXXXX, XFXXXX, XIXXXX, XJXXXX, YEXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Endocrinology, Application > Therapeutics, TherapeuticArea > Infectious Disease, TherapeuticArea > Cardiology, ResearchProducts > Computational models/software, Application > Non-Medical Devices, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Ophthalmology, TherapeuticArea > Oncology, Application > Software / Apps, Application > Occupational Safety and Health, Application > Medical Devices, TherapeuticArea > Pulmonology, Application > Research Materials, Application > Diagnostics
Methods for the Simultaneous Detection of Multiple Analytes
CDC researchers have developed a method of simultaneously detecting and distinguishing multiple antigens within a biological sample. Epidemiological and vaccine studies require species serotype identification. Current methods of serotyping are labor intensive and can easily give subjective, errant results. This technology utilizes serotype specific...
Published: 7/25/2024   |   Inventor(s): George Carlone, Joseph Martinez
Keywords(s): AA5XXX, AAXXXX, ANALYTES, AXXXXX, Bead, Beads, CA1BXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, DA1XXX, DA2XXX, DA3XXX, DA4AXX, DA4BXX, DA4XXX, DA5XXX, DAXXXX, Detection, flow cytometer, flow cytometry, IAXXXX, IMMUNOASSAY, Methods, MULTIPLE, SIMULTANEOUS, VBXXXX, VJXXXX, VKXXXX, VLXXXX, VOXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WIXXXX, WMXXXX, XAXXXX, XCXXXX, XHXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Immunology, TherapeuticArea > Oncology, Application > Consumer Products, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Infectious Disease, ResearchProducts > Research Equipment, Application > Research Materials, Application > Diagnostics, ResearchProducts > Antibodies, Application > Occupational Safety and Health
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