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Hearing Safety Devices: System for Monitoring Exposure to Impulse Noise

This CDC-developed technology entails a system for monitoring and assessing the risk of auditory damage from exposure to impulse noise, such as noise created by construction machinery and firearms. Noise dosimeters have been used extensively over the past two decades to document personal exposure to noise and assure workplaces comply with permissible...

Published: 7/25/2024 | Inventor(s): Chucri Kardous

Keywords(s): AA5XXX, AAXXXX, AC1XXX, AC2XXX, ADXXXX, AE1BXX, AE1XXX, AE2BXX, AE2XXX, AE3XXX, AEXXXX, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Exposure, firearm, firearm safety, IMPULSE, MONITORING, NIOSH, NIOSH-DART, NOISE, Occupational health, SAFETY, Sampling, System, VPXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, WMXXXX, XDXXXX, XIXXXX, XJXXXX, YEXXXX

Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, ResearchProducts > Computational models/software, Application > Research Materials, TherapeuticArea > Cardiology, TherapeuticArea > Ophthalmology, TherapeuticArea > Endocrinology, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, Application > Software / Apps, Application > Non-Medical Devices, Application > Medical Devices

Improved Acoustic Plethysmograph System for Noninvasive Measurement of Pulmonary Function

CDC researchers have developed a novel acoustic whole body plethysmograph (AWBP) that allows measurement of tidal volume in lab animals, independent of gas compression in the lung. This system provides particular advantages over the traditional whole body plethysmograph (WBP) when measuring model animals with increased gas compression due to increased...

Published: 7/25/2024 | Inventor(s): David Frazer, Jeffrey Reynolds

Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC1XXX, AC2XXX, AC3XXX, AC6XXX, Acoustic, ACXXXX, ADXXXX, AE1BXX, AE1XXX, AE3XXX, AE4XXX, AEXXXX, ANIMAL, Animal Model, ANIMAL welfare, ASTHMA, Breath, BREATHING, CDC Docket Import, CDC Docket Import CDC Prosecuting, DDXXXX, DEVICE, DEXXXX, DXXXXX, FUNCTION, IA3XXX, IA5XXX, ICXXXX, IDXXXX, LUNG, lung cancer, Lung Disease, LUNGS, Lung-Targeted, Measuring, NIOSH, NIOSH-HELD, Plethysmograph, Pulmonary, Pulmonary edema, PULMONARY FIBROSIS, research, RESEARCH TOOL, RESPIRABLE, Respiration, respiratory, Respiratory Diseases, respiratory INFECTION, Tool, VBXXXX, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WGXXXX, WIXXXX, WMXXXX, XDXXXX, XHXXXX, XIXXXX, XJXXXX, YCXXXX, YEXXXX, YFXXXX

Category(s): Collaboration Sought > Licensing, Application > Software / Apps, Application > Medical Devices, Application > Diagnostics, TherapeuticArea > Pulmonology, TherapeuticArea > Immunology, Application > Research Materials, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Vaccines, Application > Therapeutics, Application > Occupational Safety and Health, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, ResearchProducts > Computational models/software, TherapeuticArea > Oncology

Multiplex Assay for Rapid Salmonella Serotyping from Human, Animal, Food and Environmental Sources

CDC researchers have developed a bead-based nucleic acid assay for serotyping members of the Salmonella genus; this assay will identify serotypes for approximately 95% of all human-obtained Salmonella isolates in the United States. Presently, production and quality control for the more than 250 antisera required to cover the >2,500 known serotypes using...

Published: 7/25/2024 | Inventor(s): John McQuiston, Collette Fitzgerald Leaumont, Patricia Fields

Keywords(s): AA5XXX, AAXXXX, AFXXXX, assay, Bead, Beads, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, diagnostic, Diagnostic assay, DXXXXX, FOOD, FOOD PATHOGEN, FOOD-ASSOCIATED, Foodborne, ivd, NAT, Nucleic, OID-NCEZID-DFWED, PLATE-BASED, RAPID, SALMONELLA, Serotype, SEROTYPING, VETERINARY, VJXXXX, VOXXXX, WBXXXX, WCXXXX, WFXXXX, WMXXXX, XEXXXX, YBXXXX, Zoonotic

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Diagnostics, Application > Occupational Safety and Health

Methods for the Simultaneous Detection of Multiple Analytes

CDC researchers have developed a method of simultaneously detecting and distinguishing multiple antigens within a biological sample. Epidemiological and vaccine studies require species serotype identification. Current methods of serotyping are labor intensive and can easily give subjective, errant results. This technology utilizes serotype specific...

Published: 7/25/2024 | Inventor(s): George Carlone, Joseph Martinez

Keywords(s): AA5XXX, AAXXXX, ANALYTES, AXXXXX, Bead, Beads, CA1BXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, DA1XXX, DA2XXX, DA3XXX, DA4AXX, DA4BXX, DA4XXX, DA5XXX, DAXXXX, Detection, flow cytometer, flow cytometry, IAXXXX, IMMUNOASSAY, Methods, MULTIPLE, SIMULTANEOUS, VBXXXX, VJXXXX, VKXXXX, VLXXXX, VOXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WIXXXX, WMXXXX, XAXXXX, XCXXXX, XHXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Immunology, TherapeuticArea > Oncology, Application > Consumer Products, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Infectious Disease, ResearchProducts > Research Equipment, Application > Research Materials, Application > Diagnostics, ResearchProducts > Antibodies, Application > Occupational Safety and Health

Methods of Retaining Methylation Pattern Information in Globally Amplified DNA

CDC researchers have developed a novel method that generates globally amplified DNA copies retaining parental methylation information; making accurate DNA-archiving for methylation studies much more feasible and cost-effective than undertaking such an endeavor with alternate technologies. This unique approach eliminates a significant bottleneck in...

Published: 7/25/2024 | Inventor(s): Elizabeth Unger, Mangalathu Rajeevan

Keywords(s): AA5XXX, AAXXXX, AC4XXX, AC5XXX, AC6XXX, ACXXXX, AG2XXX, Amplified, AXXXXX, CC1XXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA1XXX, DA2XXX, DA3XXX, DA4AXX, DA4BXX, DA4XXX, DA5XXX, DAXXXX, DDXXXX, DNA, GAXXXX, GCXXXX, Globally, Method, Methylation, NA2BXX, NC3XXX, NC4XXX, NC5XXX, OID-NCEZID-DHCPP, Pattern, RETAINING, VAXXXX, VBXXXX, VCXXXX, VDXXXX, VEXXXX, VFXXXX, VGXXXX, VHXXXX, VIXXXX, VJXXXX, VKXXXX, VLXXXX, VMXXXX, VNXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WIXXXX, WMXXXX, XBXXXX, XCXXXX, XEXXXX, XHXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, ResearchProducts > Computational models/software, TherapeuticArea > Cardiology, TherapeuticArea > Psychiatry/Mental Health, Application > Consumer Products, TherapeuticArea > Oncology, TherapeuticArea > Neurology, Application > Therapeutics, TherapeuticArea > Geriatrics, TherapeuticArea > Ophthalmology, TherapeuticArea > Immunology, TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Vaccines, Application > Software / Apps, TherapeuticArea > Infectious Disease, Application > Research Materials, ResearchProducts > Research Equipment, Application > Diagnostics, Application > Occupational Safety and Health

Novel One-Well Limiting-Antigen Avidity Enzyme Immunoassay to Detect Recent HIV-1 Infection Using a Multi-subtype Recombinant Protein

This CDC developed Limiting-Antigen avidity Enzyme Immunoassay (LAg-avidity-EIA) provides an easy way to measure increasing binding strength (avidity) of HIV antibodies as part of maturation HIV antibodies after seroconversion, providing a method to distinguish early-stage from long-term HIV-1 infection. Surveillance of HIV-1 provides information on...

Published: 7/25/2024 | Inventor(s): Bharat Parekh

Keywords(s): AA5XXX, AAXXXX, Avidity, Avidity-EIA, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, CGH-DGHA, DA4AXX, DA4XXX, DAXXXX, DDXXXX, Detect, Development, DXXXXX, Enzyme, HIV, IMMUNOASSAY, Infection, Inmunoassay, LAg, Limiting-antigen, Listed LPM Houze as of 4/15/2015, Multi-subtype, NCHHSTP, One-well, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Protein, RECENT, recombinant, RIDR-M, VLXXXX, WBXXXX, WFXXXX, WIXXXX, XAXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Immunology, Application > Diagnostics, ResearchProducts > Antibodies, Application > Therapeutics, Application > Occupational Safety and Health, Application > Research Materials

Photoinduced Electron Transfer Fluorescent Primer for Nucleic Acid Amplification

CDC scientists have developed a rapid and cost-efficient method for generating fluorescently labeled primers for PCR and real-time PCR. At present, fluorescent primers are useful for detecting and identifying microbes and specific nucleic acid sequences, amplifying nucleic acids for pyro-sequencing, determining the levels of gene expression, and many...

Published: 7/25/2024 | Inventor(s): Vincent Hill, Brian Holloway, Jothikumar Narayanan

Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC4XXX, AC5XXX, AC6XXX, Acid, ACXXXX, AE1BXX, AG1XXX, amplification, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, ELECTRON, Nucleic, OID-NCEZID-DFWED, PET, PHOTOINDUCED, PRIMER, TRANSFER, VAXXXX, VBXXXX, VCXXXX, VDXXXX, VEXXXX, VGXXXX, VHXXXX, VIXXXX, VJXXXX, VKXXXX, VLXXXX, VMXXXX, VNXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WHXXXX, WIXXXX, WMXXXX, XBXXXX, XCXXXX, XEXXXX, XHXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, ResearchProducts > Research Equipment, Application > Diagnostics, Application > Occupational Safety and Health, Application > Research Materials, TherapeuticArea > Oncology, ResearchProducts > Computational models/software, TherapeuticArea > Neurology, TherapeuticArea > Cardiology, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Psychiatry/Mental Health, TherapeuticArea > Immunology, Application > Software / Apps, Application > Vaccines, TherapeuticArea > Infectious Disease, TherapeuticArea > Geriatrics

Virus Microneutralization Assay Data Analysis for Vaccine Development, Enhancement and Efficacy Improvement

This CDC generated invention entails improved methods of analyzing microneutralization assays, especially for the purposes of determining specific antibody concentrations and optimizing vaccine formulation. More specifically, the invention is a set of SAS based programs using 4-parameter logistic curve fitting algorithms to interpolate between individual...

Published: 4/8/2024 | Inventor(s): Kathy Hancock, Jarad Schiffer

Keywords(s): AA5XXX, AD3XXX, ADXXXX, analysis, assay, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, CONSTRAINTS, CURVE-FITTING, DA4XXX, DAXXXX, DB4XXX, DBXXXX, MICRONEUTRALIZATION, OID-NCIRD-DBD, VBXXXX, VKXXXX, VLXXXX, VOXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WHXXXX, WJXXXX, WMXXXX, XAXXXX, XHXXXX, XJXXXX, YBXXXX, YEXXXX

Category(s): Collaboration Sought > Licensing, ResearchProducts > Antibodies, TherapeuticArea > Immunology, Application > Research Materials, Application > Software / Apps, ResearchProducts > Research Equipment, Application > Diagnostics, TherapeuticArea > Infectious Disease, Application > Occupational Safety and Health, ResearchProducts > Computational models/software, Application > Therapeutics, Application > Vaccines, Application > Consumer Products

Fluorescent Primer(s) Creation for Nucleic Acid Detection and Amplification

CDC researchers have developed technology that consists of a simple and inexpensive technique for creating fluorescent labeled primers for nucleic acid amplification. Fluorescent chemical-labeled probes and primers are extensively used in clinical and research laboratories for rapid, real-time detection and identification of microbes and genetic sequences....

Published: 7/25/2024 | Inventor(s): Vincent Hill, Jothikumar Narayanan

Keywords(s): AA5XXX, AAXXXX, AC3XXX, AC4XXX, AC5XXX, Acid, ACXXXX, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Detection, Nucleic, OID-NCEZID-DFWED, PRIMER, VAXXXX, VBXXXX, VCXXXX, VDXXXX, VEXXXX, VFXXXX, VGXXXX, VHXXXX, VIXXXX, VJXXXX, VKXXXX, VLXXXX, VMXXXX, VNXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WIXXXX, XBXXXX, XEXXXX, XHXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Occupational Safety and Health, TherapeuticArea > Ophthalmology, Application > Vaccines, Application > Therapeutics, ResearchProducts > Computational models/software, Application > Research Materials, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, TherapeuticArea > Psychiatry/Mental Health, Application > Consumer Products, TherapeuticArea > Immunology, TherapeuticArea > Infectious Disease, TherapeuticArea > Geriatrics, TherapeuticArea > Neurology, ResearchProducts > Research Equipment, Application > Software / Apps

Exposure and Activity Detection Assays for Anthrax Lethal Factor and Lethal Toxin

This CDC developed invention identifies an assay for extremely fast and sensitive detection of Bacillus anthracis lethal toxin (LTx), the toxin responsible for the lethal effects of anthrax infection. This assay has already been successfully tested in animals and will allow for early detection of anthrax exposure and screening of lethal factors to...

Published: 7/25/2024 | Inventor(s): Conrad Quinn, John Barr, Anne Boyer

Keywords(s): 02706, AA5XXX, AAXXXX, Anthrax, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DA5XXX, DAXXXX, Detection, Diagnosis, diagnostic, Diagnostic assay, diagnostic in vitro, DXXXXX, FACTORS, I01306, I-013-06, I-027-06, ONDIEH-NCEH, Pathogenicity, VBXXXX, VJXXXX, VOXXXX, WAXXXX, WBXXXX, WFXXXX, WHXXXX, WIXXXX, WJXXXX, WKXXXX, WMXXXX, XAXXXX, XCXXXX, YBXXXX, YCXXXX, YDXXXX, YEXXXX

Category(s): Collaboration Sought > Licensing, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Infectious Disease, TherapeuticArea > Immunology, Application > Consumer Products, ResearchProducts > Antibodies, Application > Research Materials, Application > Occupational Safety and Health, Application > Diagnostics

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