Search Results - research+tool

8 Results

Sort By:

Software System for Analysis of Extremely Large Experimental Dataset and Multidimensional Drug Discovery

Abstract: The National Institute on Aging, Laboratory of Neurosciences-Receptor Pharmacology Unit is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize biomedical informatics. This invention is a computer software suite that will enable its user to investigate...

Published: 7/25/2024 | Inventor(s): Stuart Maudsley, Tie Yi, Bronwen Martin

Keywords(s): gene arrays, proteomics, RESEARCH TOOL, software

Category(s): Application > Research Materials, Collaboration Sought > Licensing

Methods for Single Cell Analysis of the Epigenome, Transcriptome, and Genome

Abstract: There are currently no methodologies that allow for epigenome, genome and transcriptome analysis all in a single cell. In addition, there are currently no methodologies that permit repeating the results of these analyses on the same single cells. Scientists at the National Cancer Institute (NCI) Laboratory of Cellular Oncology have developed...

Published: 4/8/2024 | Inventor(s): Giovanna Tosato, Hidetaka Ohnuki

Keywords(s): diagnostic, Epigenomic, Genomic, RESEARCH TOOL, Single Cell Analysis, Tosato, Transcriptomic

Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology

Osmogels: A New Method for Stabilizing Weak Molecular Complex Interactions

Abstract: The Eunice Kennedy Schriver National Institute of Child Health and Human Development is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize a new method for stabilizing molecular complexes in polyacrylamide gels. This invention describes a new method...

Published: 7/25/2024 | Inventor(s): Nina Sidorova, Donald Rau

Keywords(s): Diagnostic Assays Kits and/or Regeants, Electrophoretic Mobility Shift Assay, Osmogels, Polyacrylamide Gels, RESEARCH TOOL

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Research Materials

Mouse Xenograft Model for Mesothelioma

Abstract: The National Cancer Institute is seeking parties interested in collaborative research to co-develop, evaluate, or commercialize a new mouse model for monoclonal antibodies and immunoconjugates that target malignant mesotheliomas. Applications of the technology include models for screening compounds as potential therapeutics for mesothelioma...

Published: 7/25/2024 | Inventor(s): Mitchell Ho

Keywords(s): ASBESTOS, CANCER, Immunoconjugate, malignant mesothelioma, mouse model, RESEARCH TOOL, SS1P

Category(s): TherapeuticArea > Oncology, Application > Research Materials, Collaboration Sought > Licensing

WR (Western Reserve) Strain of Vaccinia Virus with K151E Mutation in A34R Gene

Mutation in gene A34R can regulate the release of progeny virions from the surface of parental cells.

Published: 7/25/2024 | Inventor(s): Rafael Blasco, Bernard Moss

Keywords(s): A34, AC4XXX, AC5XXX, ACXXXX, AXXXXX, Cell, DDXXXX, DISSOCIATION, DXXXXX, GCXXXX, GLYCOPROTEIN, MEMBRANE, Progeny, REGULATED, research, RESEARCH MATERIAL, research reagent, RESEARCH TOOL, RM, RXXXXX, vaccinia, viral, virus, WIXXXX, XEXXXX, XKXXXX

Category(s): Collaboration Sought > Licensing, Application > Vaccines, Application > Therapeutics, Application > Research Materials, TherapeuticArea > Infectious Disease

Improved Acoustic Plethysmograph System for Noninvasive Measurement of Pulmonary Function

CDC researchers have developed a novel acoustic whole body plethysmograph (AWBP) that allows measurement of tidal volume in lab animals, independent of gas compression in the lung. This system provides particular advantages over the traditional whole body plethysmograph (WBP) when measuring model animals with increased gas compression due to increased...

Published: 7/25/2024 | Inventor(s): David Frazer, Jeffrey Reynolds

Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC1XXX, AC2XXX, AC3XXX, AC6XXX, Acoustic, ACXXXX, ADXXXX, AE1BXX, AE1XXX, AE3XXX, AE4XXX, AEXXXX, ANIMAL, Animal Model, ANIMAL welfare, ASTHMA, Breath, BREATHING, CDC Docket Import, CDC Docket Import CDC Prosecuting, DDXXXX, DEVICE, DEXXXX, DXXXXX, FUNCTION, IA3XXX, IA5XXX, ICXXXX, IDXXXX, LUNG, lung cancer, Lung Disease, LUNGS, Lung-Targeted, Measuring, NIOSH, NIOSH-HELD, Plethysmograph, Pulmonary, Pulmonary edema, PULMONARY FIBROSIS, research, RESEARCH TOOL, RESPIRABLE, Respiration, respiratory, Respiratory Diseases, respiratory INFECTION, Tool, VBXXXX, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WGXXXX, WIXXXX, WMXXXX, XDXXXX, XHXXXX, XIXXXX, XJXXXX, YCXXXX, YEXXXX, YFXXXX

Category(s): Collaboration Sought > Licensing, Application > Software / Apps, Application > Medical Devices, Application > Diagnostics, TherapeuticArea > Pulmonology, TherapeuticArea > Immunology, Application > Research Materials, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Vaccines, Application > Therapeutics, Application > Occupational Safety and Health, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, ResearchProducts > Computational models/software, TherapeuticArea > Oncology

Image Analysis Software for Quantitative Evaluation of Striation Patterns and their Defects in Skeletal Muscles

Available for licensing is software written in MatLab for evaluating striation patters in images of skeletal muscle fibers for better sensitivity in the quantitation of skeletal muscle disorders. Skeletal muscles have a regular, periodic organization (the periodicity of the sarcomeres), which is not only structural but also functional. Muscle pathologies...

Published: 7/30/2024 | Inventor(s): Evelyn Ralston, Wenhua Liu

Keywords(s): AD1XXX, AD3XXX, ADXXXX, AXXXXX, MATLAB, MATLAB-based, RESEARCH TOOL, Skeletal Muscle, software

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Immortalized Stria Vascularis Cell Line SV-k1

Available for nonexclusive licensing for research uses is the cell line, SV-k1, derived from the Organ of Corti. The line was developed from the stria vascularis, an organ localized on the lateral wall of the cochlea, adjacent to the Organ of Corti, containing cell populations specialized in the production of an endolymph very rich in K+ characteristic...

Published: 7/25/2024 | Inventor(s): Federico Kalinec, Gilda Canseco De Kalinec

Keywords(s): ID1XXX, IDXXXX, immortalized, RESEARCH MATERIAL, research reagent, RESEARCH TOOL, Stria, SV-k1, Vascularis, VPXXXX, WIXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Ophthalmology, Application > Research Materials, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, TherapeuticArea > Dental