Search Results - pulmonary

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Hybrid Computer Tomography Scanning System

The invention relates to a combination hybrid computer tomography (CT) system that is particularly suited for elucidating stages in pulmonary diseases, notably cystic fibrosis and lung cancer. Improved visualization of lung parenchyma and the margins of lung cysts (non-invasive “virtual biopsy”) may provide sufficient detail to distinguish the types...

Published: 7/25/2024 | Inventor(s): Han Wen

Keywords(s): AA3B6X, AA3CXX, CT, HYBRID, lung cancer, Lung Disease, Lung-Targeted, Pulmonary, PULMONARY FIBROSIS, WBXXXX, XFXXXX, X-RAY, YAXXXX

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Medical Devices, Application > Non-Medical Devices, Application > Software / Apps

Improved Acoustic Plethysmograph System for Noninvasive Measurement of Pulmonary Function

CDC researchers have developed a novel acoustic whole body plethysmograph (AWBP) that allows measurement of tidal volume in lab animals, independent of gas compression in the lung. This system provides particular advantages over the traditional whole body plethysmograph (WBP) when measuring model animals with increased gas compression due to increased...

Published: 7/25/2024 | Inventor(s): David Frazer, Jeffrey Reynolds

Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC1XXX, AC2XXX, AC3XXX, AC6XXX, Acoustic, ACXXXX, ADXXXX, AE1BXX, AE1XXX, AE3XXX, AE4XXX, AEXXXX, ANIMAL, Animal Model, ANIMAL welfare, ASTHMA, Breath, BREATHING, CDC Docket Import, CDC Docket Import CDC Prosecuting, DDXXXX, DEVICE, DEXXXX, DXXXXX, FUNCTION, IA3XXX, IA5XXX, ICXXXX, IDXXXX, LUNG, lung cancer, Lung Disease, LUNGS, Lung-Targeted, Measuring, NIOSH, NIOSH-HELD, Plethysmograph, Pulmonary, Pulmonary edema, PULMONARY FIBROSIS, research, RESEARCH TOOL, RESPIRABLE, Respiration, respiratory, Respiratory Diseases, respiratory INFECTION, Tool, VBXXXX, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WGXXXX, WIXXXX, WMXXXX, XDXXXX, XHXXXX, XIXXXX, XJXXXX, YCXXXX, YEXXXX, YFXXXX

Category(s): Collaboration Sought > Licensing, Application > Software / Apps, Application > Medical Devices, Application > Diagnostics, TherapeuticArea > Pulmonology, TherapeuticArea > Immunology, Application > Research Materials, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Vaccines, Application > Therapeutics, Application > Occupational Safety and Health, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, ResearchProducts > Computational models/software, TherapeuticArea > Oncology

Methods for Amelioration and Treatment of Pathogen-associated Inflammatory Response

This CDC invention provides methods for preventing or treating inflammatory response-linked, infection induced pathologies, which are mediated by endogenous substance P. Substance P is a naturally-occurring and major pro-inflammatory neuromediator or neuromodulator, and elevated levels of substance P have been implicated in numerous inflammation-associated...

Published: 7/25/2024 | Inventor(s): Larry Anderson, Deborah Moore, Ralph Tripp

Keywords(s): bronchoilitis, CAUSED, CDC Docket Import, CDC Docket Import CDC Prosecuting, DB3XXX, DB4XXX, DBXXXX, DISEASES, DXXXXX, IB3XXX, Infection, Inflammation, INFLAMMATORY, Methods, nitric oxide, OID-NCIRD-DVD, P, Pain, pain control, Prevention, Pulmonary, RESPONSE, RSV, RSV virus, SUBSTANCE, SUBSTANCE p, treatment, treatment methods, vasodilation, VASODILATOR, VAXXXX, VBXXXX, VDXXXX, VEXXXX, VJXXXX, VKXXXX, VLXXXX, VMXXXX, VOXXXX, VPXXXX, WAXXXX, WIXXXX, WJXXXX, WKXXXX, WMXXXX, XAXXXX, XCXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Ophthalmology, TherapeuticArea > Infectious Disease, TherapeuticArea > Cardiology, TherapeuticArea > Oncology, Application > Consumer Products, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, Application > Vaccines, ResearchProducts > Antibodies, TherapeuticArea > Immunology, TherapeuticArea > Neurology, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Geriatrics

Select M. tuberculosis Peptides as Mucosal Vaccines Against Pulmonary Tuberculosis

This CDC-developed technology relates to novel vaccines or boosters directed against pulmonary tuberculosis. There is currently only a single vaccine against tuberculosis, the (Bacillus Calmette-Guérin) BCG vaccine. Reports suggest widely variable effectiveness for the BCG vaccine and that BCG administration has very limited success against prevention...

Published: 7/25/2024 | Inventor(s): Bonnie Plikaytis, Thomas Shinnick, Rama Amara, Mani Cheruvu, Suraj Sable

Keywords(s): Alaine, ANTIGEN, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, DC1XXX, DC4XXX, DCXXXX, DXXXXX, Identification, Mucosal, MYCOBACTERIUM, OID-NCHHSTP-DTE, PROLINE, Pulmonary, respiratory, Respiratory Diseases, respiratory INFECTION, Rich, TUBERCULOSIS, Vaccine, VACCINE DEVELOPMENT, VJXXXX, VPXXXX, WIXXXX, WJXXXX, XCXXXX, XEXXXX, XHXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Vaccines, Application > Research Materials, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology, Application > Diagnostics, TherapeuticArea > Dental, TherapeuticArea > Ophthalmology, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease, ResearchProducts > Research Equipment

Intranasal Nebulizer with Disposable Drug Cartridge for Improved Delivery of Vaccines and Therapeutics

Intranasal delivery is a simple, inexpensive and needle-free route for administration of vaccines and therapeutics. This intranasal delivery technology, developed with Creare LLC., includes low-cost, disposable drug cartridges (DDCs) that mate with a durable hand-held device. The rechargeable-battery-powered device transmits ultrasonic energy to the...

Published: 7/25/2024 | Inventor(s): James Barry, Nabil Elkouh, Mark Bagley, Darin Knaus, Robert Trabka, Eric Friets, James Norris, Mark Papania

Keywords(s): AB1XXX, AB3FXX, AB3GXX, AB3XXX, AB4XXX, Able, ABXXXX, AC1XXX, ACXXXX, AEROSOL, AEROSOL-GENERATING, AEROSOLIZATION, Aerosolized, AEROSOLS, AXXXXX, BACTERIA, Bacterial, BACTERIAL VACCINES, CARTRIDGE, CDC, CDC Docket Import, CDC Docket Import CDC Prosecuting, Chamber, COOLING, DB1XXX, DB2XXX, DB3XXX, DB4XXX, DB5XXX, DBXXXX, DC1XXX, DC2XXX, DC3XXX, DC4XXX, DC5BXX, DC5XXX, DC6XXX, DCXXXX, Delivery, DEVICE, Devices, Disposable, DRUG, Drug Delivery, DXXXXX, FUNGAL, HAND, Having, INSERT, Intranasal, Methods, NASAL, NEBULIZER, NIOSH-PRL, OID-NCIRD-DVD, PLATFORM, Platforms, Pulmonary, respiratory, Respiratory Diseases, respiratory INFECTION, System, SYSTEMS, therapeutic, therapeutic delivery, Vaccine, VACCINE DELIVERY, Vaccine Design, VACCINE DEVELOPMENT, VBXXXX, viral, viral vaccine, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WFXXXX, WJXXXX, WKXXXX, WMXXXX, XDXXXX, YBXXXX, YCXXXX, YFXXXX

Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, Application > Medical Devices, Application > Diagnostics, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Consumer Products, TherapeuticArea > Oncology

Human Influenza Virus Real-time RT-PCR Detection and Characterization Panel

This invention relates to methods of rapidly detecting influenza, including differentiating between type and subtype. Unlike culture and serological tests requiring 5 to 14 days for completion, CDC researchers developed a rapid, accurate assay, which is easily adapted to kit form. This assay also requires less labor input than immunoassays. These...

Published: 7/25/2024 | Inventor(s): Alexander Klimov, Nancy Cox, Lamorris Loftin, Stephen Lindstrom

Keywords(s): Avian, Avian flu, Avian influenza, CDC, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA4BXX, DA4XXX, DAXXXX, DDXXXX, Detection, DEVELOPED, DEVELOPING, Discriminate, discrimination, DXXXXX, INFLUENZA, PCR, PRIMERS, Probes, Pulmonary, respiratory, Respiratory Diseases, respiratory INFECTION, RT-PCR, Serotypes, SUBTYPES, Swine, tropical, Types, VETERINARY, viral, virus, Viruses, VLXXXX, VOXXXX, WBXXXX, WFXXXX, WMXXXX, XCXXXX, XEXXXX, YBXXXX, Zoo, Zoonotic

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics, Application > Consumer Products, Application > Occupational Safety and Health, Application > Diagnostics, Application > Research Materials

Defensin-Based Therapeutics for the Treatment of Pulmonary Disease

Investigators at the National Heart, Lung and Blood Institute have developed modified defensins that are resistant to degradation, have improved characteristics compared to unmodified defensins, and are promising candidates for pulmonary disease therapeutics. Defensins are small cationic peptides that defend the lung against pathogenic microorganisms...

Published: 7/25/2024 | Inventor(s): Joel Moss

Keywords(s): ADP-ribose, ADP-ribose-arginine, ADP-RIBOSYLARGININE, ADP-ribosylation, AIRWAY, Arginines, ASTHMA, BBXXXX, cytotoxic, CYTOTOXICITY, DBXXXX, defensin, Defensins, DXXXXX, HNP-1, human neutrophil peptide 1, IB4XXX, IBXXXX, Inflammation, IXXXXX, neutrophil, Patent Category - Biotechnology, Pulmonary, PULMONARY FIBROSIS

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics, TherapeuticArea > Pulmonology, Application > Diagnostics, Application > Research Materials