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Electronic Fringe Scanning for the Improvement of Medical Imaging Technology

This technology includes an electronic method for fringe scanning in grating-based phase-contrast imaging, which enhances x-ray phase-contrast imaging. Traditional methods use high-density gratings and require fine grating fringes, finer than the detector's resolution, necessitating fringe scanning to obtain phase-contrast information. This process...

Published: 8/12/2024 | Inventor(s): Han Wen

Keywords(s):

Category(s): Application > Medical Devices, Collaboration Sought > Licensing, ResearchProducts > Research Equipment

Hybrid Computer Tomography Scanning System

The invention relates to a combination hybrid computer tomography (CT) system that is particularly suited for elucidating stages in pulmonary diseases, notably cystic fibrosis and lung cancer. Improved visualization of lung parenchyma and the margins of lung cysts (non-invasive “virtual biopsy”) may provide sufficient detail to distinguish the types...

Published: 7/25/2024 | Inventor(s): Han Wen

Keywords(s): AA3B6X, AA3CXX, CT, HYBRID, lung cancer, Lung Disease, Lung-Targeted, Pulmonary, PULMONARY FIBROSIS, WBXXXX, XFXXXX, X-RAY, YAXXXX

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Medical Devices, Application > Non-Medical Devices, Application > Software / Apps

A Novel X-ray Grating to Enhance Phase Contrast Imaging

The present invention relates to improving x-ray phase contrast imaging. The invention discloses a novel grating interferometer for phase contrast imaging with hard x-rays that overcomes limitations in the level of sensitivity by utilizing the advantages of far-field interferometers. The novel design and fabrication process can easily acquire absolute...

Published: 7/25/2024 | Inventor(s): Han Wen

Keywords(s): AA3XXX, Balanced, GRATING, INTERFEROMETER, Two-arm, VCXXXX, VDXXXX, WBXXXX, WIXXXX, XDXXXX, XFXXXX, X-RAY, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, Application > Software / Apps, Application > Medical Devices, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Oncology

A Novel Demodulation System in X-ray Imaging

In various x-ray imaging methods, including scattering correction and phase contrast imaging, intensity modulation in space is introduced into the projection images by the use of masks, gratings, or apertures. The present invention relates to a process to demodulate the modulation. The current demodulation processes are either to remove the modulation...

Published: 7/25/2024 | Inventor(s): Houxun Miao, Han Wen

Keywords(s): AA3XXX, Demodulation, IMAGING, INTENSITY, Modulation, VCXXXX, VDXXXX, VEXXXX, VPXXXX, WBXXXX, WIXXXX, XDXXXX, XFXXXX, X-RAY, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Ophthalmology, TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Software / Apps, TherapeuticArea > Neurology, Application > Research Materials, Application > Diagnostics, Application > Medical Devices

Multilayer X-Ray Transmission Grating Array for Phase-Contrast Imaging and Tomography

Classical X-ray Computed Tomography (CT) and radiography are based on X-ray absorption and cannot show soft tissue structures as well as Magnetic Resonance Imaging (MRI). Detecting the phase delay/advance of X-rays that travel through the body could enhance soft tissue contrast 10 - 100 times. Submicron-period X-ray transmission gratings for medical...

Published: 4/8/2024 | Inventor(s): Han Wen

Keywords(s): AA3XXX, AAXXXX, ARRAY, AXXXXX, GRATING, IMAGING, MICRO, Multilayer-coated, PHASE, SENSITIVE, X-RAY

Category(s): Collaboration Sought > Collaboration

Signal-to-Noise Enhancement in Imaging Applications Using a Time-Series of Images

The invention offered for licensing relates to the field of imaging and specifically to the field of medical imaging. The apparatus and method of the invention provide for noise reduction in imaging applications that use a time-series of images. In one embodiment of the invention, a time-series of images is acquired using a same imaging protocol of...

Published: 7/25/2024 | Inventor(s): Vinay Pai, Han Wen

Keywords(s): Acquisitions, analysis, COMBINED, COMPONENT, ENHANCEMENT, IA4BXX, IA4XXX, IAXXXX, IMAGING, INTENSITY, IXXXXX, LOW, Magnetic, Maximal, Method, Patent Category - Mech/Elect/Soft, PCA, PRINCIPAL, PROJECTION, Resonance, Signal, Signal-to-Noise, TEMPORAL, tMIP

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, Application > Therapeutics

Fluorescent Nanodiamonds as Fiducial Markers for Microscopy

The invention relates to fluorescent nanodiamonds (FNDs) and their uses as fiducial markers for microscopy. FNDs are bright fluorescent probes that do not blink or bleach and have broad fluorescence excitation and emission peaks. The fluorescence intensity can be readily controlled by the size of the FND, the number of fluorescent centers produced...

Published: 4/8/2024 | Inventor(s): Han Wen, Jennifer Hong, Chang Yi, Ambika Bumb, Susanta Sarkar, Lawrence Samelson, Asit Manna, Keir Neuman

Keywords(s): AC2XXX, AC3XXX, AC4XXX, FIDUCIAL, Fluorescence, fluorescent, IMAGING, MICROSCOPY, Nanodiamonds, nanotechnology, PXXXXX, WIXXXX, XFXXXX, XGXXXX, XHXXXX, YBXXXX

Category(s): Collaboration Sought > Collaboration, Application > Non-Medical Devices, Application > Therapeutics, Application > Consumer Products, Application > Software / Apps, ResearchProducts > Research Equipment, Application > Medical Devices, Application > Research Materials, Application > Diagnostics

Rapid Motion Perception MRI Navigator Method

Available for licensing and commercial development is a non-breathhold flow sensitive navigator technique for reducing respiratory motion artifacts in magnetic resonance (MR) images. The method, called Rapid Motion Perception (RaMP), tracks bulk translational motion of the heart in real-time. The position of the blood volume is a direct representation...

Published: 7/25/2024 | Inventor(s): Vinay Pai, Han Wen

Keywords(s): AA3AXX, AA3B1X, AA3BXX, AA3XXX, AAXXXX, AXXXXX

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Mapping Internal and Bulk Motion of an Object with Phase Labeling in Magnetic Resonance Imaging

Current MRI methods for tracking the motion of an object over a relatively long period of time requires the use of precisely defined grid points that may be inexact because of limited image resolution or the size of the element being tracked. Phase contrast velocity mapping generally provides high spatial resolution and simple data processing. However,...

Published: 7/25/2024 | Inventor(s): Anthony Aletras, Han Wen

Keywords(s): AA3AXX, AA3B1X, AA3BXX, AA3XXX, AAXXXX, AXXXXX

Category(s): Collaboration Sought > Licensing

Ultrasound-Hall Effect Imaging System And Method

The invention provides for a novel ultrasound-based imaging modality that is based on the interaction of a static magnetic field and conductive moieties in the imaged sample under electrical excitation. The invention also provides a novel ultrasound-based imaging modality that provides a contrast mechanism which reflects the conductivity distribution...

Published: 4/8/2024 | Inventor(s): Han Wen

Keywords(s): AA3B4X, AA3BXX, AA3XXX, AAXXXX, AXXXXX

Category(s): Collaboration Sought > Licensing

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