Search Results - ambika+bumb

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Background-free Imaging by Selective Modulation of Nanodiamond Fluorescence Using a Magnetic Field

This technology includes the use of nanodiamonds to achieve background-free imaging. We present several techniques to reduce or eliminate background florescence by exploiting properties of the fluorescent nanodiamonds. In particular, magnetic field modulation of the fluorescence intensity offers a simple, robust, and easily adaptable method to obtain...

Published: 8/12/2024 | Inventor(s): Ambika Bumb, Susanta Sarkar, Keir Neuman

Keywords(s):

Category(s): Application > Diagnostics, Application > Medical Devices, Application > Software / Apps, Collaboration Sought > Licensing, ResearchProducts > Computational models/software, ResearchProducts > Research Equipment

Silica-Coated Nanodiamonds for Imaging and Delivery of Therapeutic Agents

Abstract: The NCI Radiation Oncology Branch and the NHLBI Laboratory of Single Molecule Biophysics seek parties to co-develop fluorescent nanodiamonds for use as in vivo and in vitro optical tracking probes toward commercialization. NCI and NHLBI investigators invented a robust and easily implemented method of synthesizing silica-coated nanodiamonds...

Published: 4/8/2024 | Inventor(s): Ambika Bumb, Susanta Sarkar, Martin Brechbiel, Keir Neuman

Keywords(s): diagnostic, FUNCTIONALIZED, IMAGING, Nanodiamond, Silica-coated

Category(s): TherapeuticArea > Oncology, Application > Diagnostics, Collaboration Sought > Licensing

Background-Free Fluorescent Nanodiamond Imaging

Available for licensing and commercial development are intellectual property rights covering a method of imaging a biological specimen (e.g., human tissue) using fluorescent nanodiamonds implanted into the subject of interest, applying a magnetic field to said subject and producing a resultant image by a net juxtaposition of a second acquired image....

Published: 7/25/2024 | Inventor(s): Ambika Bumb, Keir Neuman

Keywords(s): AA3AXX, AA3XXX, AAXXXX, AXXXXX, Background-free, IMAGING, MRI, Nanodiamond

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Fluorescent Nanodiamonds as Fiducial Markers for Microscopy

The invention relates to fluorescent nanodiamonds (FNDs) and their uses as fiducial markers for microscopy. FNDs are bright fluorescent probes that do not blink or bleach and have broad fluorescence excitation and emission peaks. The fluorescence intensity can be readily controlled by the size of the FND, the number of fluorescent centers produced...

Published: 4/8/2024 | Inventor(s): Han Wen, Jennifer Hong, Chang Yi, Ambika Bumb, Susanta Sarkar, Lawrence Samelson, Asit Manna, Keir Neuman

Keywords(s): AC2XXX, AC3XXX, AC4XXX, FIDUCIAL, Fluorescence, fluorescent, IMAGING, MICROSCOPY, Nanodiamonds, nanotechnology, PXXXXX, WIXXXX, XFXXXX, XGXXXX, XHXXXX, YBXXXX

Category(s): Collaboration Sought > Collaboration, Application > Non-Medical Devices, Application > Therapeutics, Application > Consumer Products, Application > Software / Apps, ResearchProducts > Research Equipment, Application > Medical Devices, Application > Research Materials, Application > Diagnostics