HOME
SEARCH
RSS FEED
SUBSCRIBE
Search Results - p
1464
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Oxynitidine Derivatives Useful as Inhibitors of To
p
oisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) for Treating Cancer
Summary: The National Cancer Institute (NCI) is actively seeking
p
otential licensees and/or co-development research collaboration partners interested in advancing oxynitidine derivatives as novel inhibitors of topoisomerase IB (TOP1) and tyrosyl-DNA phosphodiesterase 1 (TDP1) for cancer treatment. These TOPI and TDP1 inhibitors, when administered...
Published: 9/18/2024
|
Inventor(s):
Yves
P
ommier
,
Lin-kun An
,
Keli Agama
,
Evgeny Kiselev
,
Azhar Ravji
Keywords(s):
Benzo
p
henanthridine Derivatives
,
Benzo
p
henanthridinone
,
Cam
p
tothecin
,
Dihydrobenzo
p
henanthridine
,
IRINOTECAN
,
Oxynitidine
,
P
ommier
,
Td
p
1
,
TO
P
1
,
To
p
oisomerase 1B
,
To
p
otecan
,
Tyrosyl-DNA
P
hosphodiesterase 1
Category(s):
Collaboration Sought > Licensing
,
Collaboration Sought > Collaboration
,
Thera
p
euticArea > Oncology
,
A
p
plication > Therapeutics
Single Source-Detector Se
p
aration Approach to Calculate Tissue Oxygen Saturation
Summary: The National Institute of Child Health and Human Develo
p
ment (NICHD) seeks partners and/or licensees to further develop and commercialize the miniaturized tissue oximeter for implementing the single source-detector separation algorithm in existing devices/systems to collect tissue oxygen saturation. Description of Technology: Tissue oxygen...
Published: 9/18/2024
|
Inventor(s):
Thien Nguyen
,
Amir Gandjbakhche
,
Soongho
P
ark
,
Brian Hill
Keywords(s):
Category(s):
A
p
plication > Medical Devices
,
Collaboration Sought > Collaboration
,
Thera
p
euticArea > Respiratory
,
Thera
p
euticArea > Neurology
,
Thera
p
euticArea > Infectious Disease
Methods of Detecting Loss of Heterozygosity and Damaging Mutations in Immune-Related Genes Using Liquid Bio
p
sies
Summary: The National Cancer Institute (NCI) seeks co-develo
p
ment partners and/or licensees for a liquid biopsy diagnostic assay capable of detecting loss of heterozygosity (LOH) and somatic mutations in genes important for antigen processing and presentation and interferon-γ response pathways. Description of Technology: Immunotherapy is...
Published: 9/13/2024
|
Inventor(s):
Scott Norberg
,
Andrew Sinkoe
,
Xiaolin Wu
,
James Gulley
Keywords(s):
Category(s):
A
p
plication > Diagnostics
,
Collaboration Sought > Collaboration
,
Thera
p
euticArea > Oncology
,
Thera
p
euticArea > Immunology
Im
p
roved Methods For Cryopreservation Of Cells, Tissues, And Organs
Summary: The National Eye Institute seeks research co-develo
p
ment partners and/or licensees for novel methods of cryopreserving cells, tissues, and organs via FOXO1 activation and other mechanisms. Description of Technology: The cornea is a critical part of the eye that helps prevent debris from entering and refracts light for proper vision. Corneal...
Published: 9/9/2024
|
Inventor(s):
Jingxing Ou
,
Kiyoharu Miyagishima
,
Guanghui Jin
,
Wei Li
,
Lihao Ge
Keywords(s):
Category(s):
A
p
plication
,
A
p
plication > Research Materials
,
Collaboration Sought > Collaboration
,
Thera
p
euticArea > Eye / Ear / Nose / Throat
Using Artificial Intelligence To Diagnose Uveitis
Summary: The National Eye Institute seeks research co-develo
p
ment partners and/or licensees for a deep learning algorithm that can identify retinal vasculitis using color fundus images. Description of Technology: Uveitis is caused by inflammation in the eye that can cause pain and reduce vision. The rate of uveitis in the United States is 1 in every...
Published: 8/14/2024
|
Inventor(s):
Shil
p
a Kodati
,
Jongwoo Kim
,
Nam Nguyen
Keywords(s):
Category(s):
A
p
plication > Diagnostics
,
Collaboration Sought > Collaboration
,
Thera
p
euticArea > Eye / Ear / Nose / Throat
Using Artificial Intelligence To
P
redict The Risk Of Age-Related Macular Degeneration
Summary: The National Eye Institute seeks research co-develo
p
ment partners and/or licensees for a deep learning algorithm that can predict the probability of progression to late age-related macular degeneration. Description of Technology: In 2024, an estimated 200 million people worldwide suffer from age-related macular degeneration (AMD); projected...
Published: 8/14/2024
|
Inventor(s):
Emily Chew
,
Zhiyong Lu
,
Tiarnan Keenan
,
Wai Wong
,
Qingyu Chen
,
Elvira Agron
Keywords(s):
Category(s):
A
p
plication > Diagnostics
,
Collaboration Sought > Collaboration
,
Thera
p
euticArea > Eye / Ear / Nose / Throat
TYROSINASE Gene Thera
p
y for Oculocutaneous Albinism type 1A
Summary: The National Eye Institute seeks research co-develo
p
ment partners and/or licensees for an adeno-associated viral gene therapy for Oculocutaneous Albinism type 1A. Description of Technology: Oculocutaneous albinism (OCA) is a genetically heterogeneous congenital disorder characterized by decreased or absent pigmentation in the hair,...
Published: 8/14/2024
|
Inventor(s):
Brian Brooks
,
Aman George
Keywords(s):
Category(s):
A
p
plication
,
A
p
plication > Therapeutics
,
Collaboration Sought > Collaboration
,
Thera
p
euticArea > Eye / Ear / Nose / Throat
,
Thera
p
euticArea > Rare / Neglected Diseases
,
Thera
p
euticArea > Ophthalmology
Interleukin-27
P
roducing B-Cell Population and Uses Thereof
Summary: The National Eye Institute (NEI) seeks research co-develo
p
ment partners and/or licensees to advance the production and uses of interleukin-27 (IL-27) producing B-regulatory cell (i27-Breg) therapy for immune related autoimmune disorders. These disorders include but are not limited, to age-related macular degeneration (AMD), graft-versus-host...
Published: 8/14/2024
|
Inventor(s):
Charles Egwuagu
,
Jin Choi
Keywords(s):
Category(s):
A
p
plication > Therapeutics
,
Collaboration Sought > Collaboration
,
Thera
p
euticArea > Eye / Ear / Nose / Throat
,
Thera
p
euticArea > Neurology
,
Thera
p
euticArea > Immunology
Using FDA-a
p
proved Small Molecule Drug Reserpine and related compounds (especially Halofantrine) To Protect Photoreceptors In Inherited Retinal Degenerations And Age-Related Macular Degeneration
Summary: The National Eye Institute seeks research co-develo
p
ment partners and/or licensees for a therapy using an FDA-approved small molecule drug reserpine (and related compounds especially halofantrine) that prevents photoreceptor cell death in retinal degenerations. Description of Technology: Inherited Retinal Degenerations (IRD), such as Leber...
Published: 9/18/2024
|
Inventor(s):
Anand Swaroo
p
,
Yu Holly Chen
,
Samantha
P
apal
,
Anu
p
am Mondal
,
Manju Swaroo
p
,
Wei Zheng
,
Gregory Tawa
,
Wenwei Huang
,
Zhiji Luo
Keywords(s):
Category(s):
A
p
plication > Therapeutics
,
Collaboration Sought > Collaboration
,
Thera
p
euticArea > Eye / Ear / Nose / Throat
Methods of Detecting Loss of Heterozygosity and Damaging Mutations in Immune-Related Genes Using Liquid Bio
p
sies
Summary: The National Cancer Institute (NCI) seeks co-develo
p
ment partners and/or licensees for a liquid biopsy diagnostic assay capable of detecting loss of heterozygosity (LOH) and somatic mutations in genes important for antigen processing and presentation and interferon-γ response pathways. Description of Technology: Immunotherapy is...
Published: 7/26/2024
|
Inventor(s):
Scott Norberg
,
Andrew Sinkoe
,
Xiaolin Wu
,
James Gulley
Keywords(s):
Category(s):
A
p
plication > Diagnostics
,
Collaboration Sought > Collaboration
,
Thera
p
euticArea > Oncology
,
Thera
p
euticArea > Immunology
1
2
3
4
5
6
7
8
9
10
...
Home
|
Search
|
RSS
|
Subscribe
© 2024. All Rights Reserved. Powered by
Inteum