Search Results - kapil+bharti

13 Results

Sort By:

Advanced Gene Editing Technology for Therapeutic Applications

The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of advanced gene editing technology for therapeutic applications. This technology includes advanced gene editing techniques aimed at developing targeted therapies for genetic disorders. Current treatments for many genetic conditions are limited,...

Published: 6/18/2026 | Updated: 6/16/2026 | Inventor(s): Ruchi Sharma, Kapil Bharti

Keywords(s):

Category(s): Application > Therapeutics, Application > Research Materials, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, ResearchProducts > Plasmids/Vectors, ResearchProducts > Sequences, TherapeuticArea > Ophthalmology, TherapeuticArea > Rare/Neglected Diseases

A Robust Method to Generate Macular vs Peripheral RPE Cells for Cell Therapy and Drug Discovery

The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of a robust method to generate macular and peripheral retinal pigment epithelium (RPE) cells for targeted therapies and drug discovery. This technology includes a robust method to generate macular and peripheral retinal pigment epithelium (RPE)...

Published: 6/18/2026 | Updated: 6/16/2026 | Inventor(s): Kapil Bharti, Fnu Ruchi, Davide Ortolan

Keywords(s):

Category(s): Application > Research Materials, Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, ResearchProducts > Human iPSC Lines, ResearchProducts > Human Cell Lines, TherapeuticArea > Ophthalmology, TherapeuticArea > Geriatrics

Biodegradable Tissue Scaffold for Multi-Tissue Transplantation

The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of a biodegradable tissue scaffold designed for multi-tissue transplantation. This technology includes a dual-layer biodegradable tissue scaffold designed for the transplantation of multiple tissue types, such as retinal pigment epithelium (RPE)...

Published: 6/18/2026 | Updated: 6/16/2026 | Inventor(s): Arvydas Maminishkis, Kapil Bharti, Davide Ortolan, Ruchi Sharma

Keywords(s):

Category(s): Application > Medical Devices, Application > Research Materials, Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Ophthalmology

iPSC Differentiation Protocol for Fibroblast and Endothelial Cell Generation

The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of a novel iPSC differentiation protocol for generating fibroblasts and endothelial cells. This technology includes a novel protocol for differentiating induced pluripotent stem cells (iPSCs) into fibroblasts and endothelial cells, which are...

Published: 6/18/2026 | Updated: 6/16/2026 | Inventor(s): Tea Soon Park, Kapil Bharti

Keywords(s):

Category(s): Application > Research Materials, Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, ResearchProducts > Human Cell Lines, ResearchProducts > Human iPSC Lines, TherapeuticArea > Ophthalmology

Thermosensitive Hydrogel Bioink for Vascular Tissue Engineering

The National Eye Institute (NEI) seeks research co-development partners and/or licensees for a thermosensitive, pro-angiogenic material designed for 3D bioprinting. This technology includes a thermosensitive hydrogel bioink designed for vascular tissue engineering. The hydrogel is unique in that it transitions from a gel state at room temperature to...

Published: 6/18/2026 | Updated: 6/16/2026 | Inventor(s): Eric Nguyen, Kapil Bharti, Min Jae Song, Marc Ferrer-Alegre, Russell Quinn

Keywords(s):

Category(s): Application > Research Materials, Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Cardiology, TherapeuticArea > Ophthalmology

Tissue Clamp for Repeated Opening and Closure of Incisions/Wounds

Abstract: Medical clamps currently available are not efficient nor are they sufficiently precise in closure and alignment of the edges of an incision or wound. Many available designs are difficult to use and handle, especially in situations where repeated opening and closure of an incision or wound is required. The functional short-comings of existing...

Published: 4/22/2025 | Updated: 8/2/2023 | Inventor(s): Vladimir Khristov, Steven Charles, Juan Amaral, Arvydas Maminishkis, Kapil Bharti

Keywords(s): CLAMP, ocular surgery, sclera incision closure

Category(s): Collaboration Sought > Collaboration, Application > Non-Medical Devices, Application > Medical Devices, Collaboration Sought > Licensing, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology

3D Vascularized Human Ocular Tissue for Cell Therapy and Drug Discovery

Abstract: Degeneration of retinal tissues occurs in many ocular disorders resulting in the loss of vision. Dysfunction and/or loss of Retinal Pigment Epithelium Cells (RPE) and disruption of the associated blood retinal barrier (BRB) tissue structures are linked with many ocular diseases and conditions including: age-related macular degeneration (AMD),...

Published: 4/22/2025 | Updated: 8/2/2023 | Inventor(s): Kapil Bharti, Min Jae Song, Russell Quinn

Keywords(s): 3D bio-printing, Bharti, Blood Retinal Barrier Disorder, BRB, Cell therapy, in Vitro Human Blood Retinal Barrier Model, Ocular cell therapy scaffold, Retinal disorder, Retinal Pigment Epithelium Cells

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology

Devices for Improved Tissue Cryopreservation and Recovery

Abstract: Problem: Cryopreservation is a process where living biological materials like cells, tissues, and cell therapies (which are susceptible to damage caused by unregulated chemical kinetics) are preserved by cooling to very low temperatures in the presence of specific cryopreservation media that protects the biological material from damage. In...

Published: 4/22/2025 | Updated: 8/2/2023 | Inventor(s): Vladimir Khristov, Arvydas Maminishkis, Kapil Bharti

Keywords(s): Cell recovery, Cell thawing, Cell therapy, Cryopreservation, Defrost, National Eye Institute, NEI, Tissue transplant

Category(s): Collaboration Sought > Materials Available, Application > Medical Devices, TherapeuticArea > Immunology, TherapeuticArea > Dermatology, Collaboration Sought > Licensing, Application > Non-Medical Devices, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology

Machine Learning and/or Neural Networks to Validate Stem Cells and Their Derivatives for Use in Cell Therapy, Drug Delivery, and Diagnostics

Abstract: Many biological and clinical procedures require functional validation of a desired cell type. Current techniques to validate rely on various assays and methods, such as staining with dyes, antibodies, and nucleic acid probes, to assess stem cell health, death, proliferation, and functionality. These techniques potentially destroy stem cells...

Published: 4/22/2025 | Updated: 8/2/2023 | Inventor(s): Kapil Bharti, Nicholas Schaub, Carl Simon, Nathan Hotaling

Keywords(s): Bharti, Cell therapy, Cell Validation, Less Invasive Diagnostics, Machine Learning, Neural Networks, QUALITY CONTROL, Stem Cell Diagnostics, Stem Cell Therapy

Category(s): TherapeuticArea > Cardiology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Software / Apps, TherapeuticArea > Dermatology

Method for Reproducible Differentiation of Clinical Grade Retinal Pigment Epithelium Cells

Abstract: The retinal pigment epithelium (RPE) is a cell monolayer with specialized functions crucial to maintaining the metabolic environment and chemistry of the sub-retinal and choroidal layers in the eye. Damage or disease causing RPE cell loss leads to progressive photoreceptor damage and impaired vision. Loss of RPE is observed in many of the...

Published: 4/22/2025 | Updated: 8/2/2023 | Inventor(s): Kapil Bharti

Keywords(s): Age Related Macular Degeneration, AMD, Best Disease, Bharti, Human Induced Pluripotent Stem Cells, Human Retinal Pigment Epithelial Cells, IPSCS, National Eye Institute, National Institute of Arthritis and Muscoskeletal and Skin D, NEI, NIAMS, Photoreceptor, Retinal Degenerative Diseases, RPE, STEM CELLS, Vision Loss

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology

1 2