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Adaptor for Suspending a Cryovial Over a Centrifuge Tube
The invention pertains to a device and system for expediting the thawing of frozen specimens (e.g., cryopreserved cells) contained in cryo-vials. An adaptor support suspends cryo-vials over a centrifuge tube containing culture medium in an inverted position. The adaptor has an elongated tubular body. While relatively basic, the adaptor dramatically...
Published: 4/8/2024   |   Inventor(s): Margaret Beddall, Pratip Chattopadhyay, Mario Roederer
Keywords(s): AC3XXX, AC4XXX, AC6XXX, ADAPTER, AFXXXX, Cells, Cryopreservation, Cryopreserved, Cryo-sample, FROZEN, Listed LPM Shmilovich as of 4/15/2015, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Thawing, WIXXXX, WMXXXX, XDXXXX, YFXXXX
Category(s): Collaboration Sought > Collaboration, Application > Consumer Products, Application > Non-Medical Devices, Application > Medical Devices, Application > Research Materials
Improved Acoustic Plethysmograph System for Noninvasive Measurement of Pulmonary Function
CDC researchers have developed a novel acoustic whole body plethysmograph (AWBP) that allows measurement of tidal volume in lab animals, independent of gas compression in the lung. This system provides particular advantages over the traditional whole body plethysmograph (WBP) when measuring model animals with increased gas compression due to increased...
Published: 7/25/2024   |   Inventor(s): David Frazer, Jeffrey Reynolds
Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC1XXX, AC2XXX, AC3XXX, AC6XXX, Acoustic, ACXXXX, ADXXXX, AE1BXX, AE1XXX, AE3XXX, AE4XXX, AEXXXX, ANIMAL, Animal Model, ANIMAL welfare, ASTHMA, Breath, BREATHING, CDC Docket Import, CDC Docket Import CDC Prosecuting, DDXXXX, DEVICE, DEXXXX, DXXXXX, FUNCTION, IA3XXX, IA5XXX, ICXXXX, IDXXXX, LUNG, lung cancer, Lung Disease, LUNGS, Lung-Targeted, Measuring, NIOSH, NIOSH-HELD, Plethysmograph, Pulmonary, Pulmonary edema, PULMONARY FIBROSIS, research, RESEARCH TOOL, RESPIRABLE, Respiration, respiratory, Respiratory Diseases, respiratory INFECTION, Tool, VBXXXX, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WGXXXX, WIXXXX, WMXXXX, XDXXXX, XHXXXX, XIXXXX, XJXXXX, YCXXXX, YEXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, Application > Software / Apps, Application > Medical Devices, Application > Diagnostics, TherapeuticArea > Pulmonology, TherapeuticArea > Immunology, Application > Research Materials, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Ophthalmology, Application > Vaccines, Application > Therapeutics, Application > Occupational Safety and Health, TherapeuticArea > Infectious Disease, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, ResearchProducts > Computational models/software, TherapeuticArea > Oncology
Focused Electrostatic Collection of Aerosol Particles for Chemical Analysis by Spectroscopic Techniques
This CDC-developed technology is an aerosol preconcentration unit (APU) designed for use with spectroscopic detection techniques, including emission, Raman, or infrared spectroscopies. Most existing pulsed microplasma techniques, such as laser-induced breakdown, for aerosols rely mainly on filter-based collection and suffer from poor accuracy, precision,...
Published: 7/25/2024   |   Inventor(s): Prasson Diwakar, Pramod Kulkarni
Keywords(s): AA2XXX, AA3AXX, AA3B5X, AA3CXX, AA3XXX, AC1XXX, AC3XXX, AC4XXX, AC6XXX, ACXXXX, ADXXXX, AE2AXX, AE2XXX, AE3XXX, AE4XXX, AEROSOL, AEXXXX, AG1XXX, ANALYSER, ANALYSES, analysis, apparatus, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, DAXXXX, DEVICE, DXXXXX, IA5XXX, IDXXXX, Method, NIOSH, NIOSH-DART, OID-NCIRD-DVD, optical, PLASMA, SPECTROSCOPY, TECHNIQUE, VBXXXX, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WEXXXX, WFXXXX, WGXXXX, WIXXXX, WMXXXX, XDXXXX, XFXXXX, XGXXXX, XHXXXX, XIXXXX, YEXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Medical Devices, ResearchProducts > Research Equipment, Application > Research Materials, Application > Occupational Safety and Health, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, TherapeuticArea > Ophthalmology, Application > Consumer Products, TherapeuticArea > Oncology, TherapeuticArea > Pulmonology, Application > Non-Medical Devices, TherapeuticArea > Infectious Disease, Application > Software / Apps, TherapeuticArea > Cardiology
Methods of Retaining Methylation Pattern Information in Globally Amplified DNA
CDC researchers have developed a novel method that generates globally amplified DNA copies retaining parental methylation information; making accurate DNA-archiving for methylation studies much more feasible and cost-effective than undertaking such an endeavor with alternate technologies. This unique approach eliminates a significant bottleneck in...
Published: 7/25/2024   |   Inventor(s): Elizabeth Unger, Mangalathu Rajeevan
Keywords(s): AA5XXX, AAXXXX, AC4XXX, AC5XXX, AC6XXX, ACXXXX, AG2XXX, Amplified, AXXXXX, CC1XXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA1XXX, DA2XXX, DA3XXX, DA4AXX, DA4BXX, DA4XXX, DA5XXX, DAXXXX, DDXXXX, DNA, GAXXXX, GCXXXX, Globally, Method, Methylation, NA2BXX, NC3XXX, NC4XXX, NC5XXX, OID-NCEZID-DHCPP, Pattern, RETAINING, VAXXXX, VBXXXX, VCXXXX, VDXXXX, VEXXXX, VFXXXX, VGXXXX, VHXXXX, VIXXXX, VJXXXX, VKXXXX, VLXXXX, VMXXXX, VNXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WIXXXX, WMXXXX, XBXXXX, XCXXXX, XEXXXX, XHXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, ResearchProducts > Computational models/software, TherapeuticArea > Cardiology, TherapeuticArea > Psychiatry/Mental Health, Application > Consumer Products, TherapeuticArea > Oncology, TherapeuticArea > Neurology, Application > Therapeutics, TherapeuticArea > Geriatrics, TherapeuticArea > Ophthalmology, TherapeuticArea > Immunology, TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Vaccines, Application > Software / Apps, TherapeuticArea > Infectious Disease, Application > Research Materials, ResearchProducts > Research Equipment, Application > Diagnostics, Application > Occupational Safety and Health
Photoinduced Electron Transfer Fluorescent Primer for Nucleic Acid Amplification
CDC scientists have developed a rapid and cost-efficient method for generating fluorescently labeled primers for PCR and real-time PCR. At present, fluorescent primers are useful for detecting and identifying microbes and specific nucleic acid sequences, amplifying nucleic acids for pyro-sequencing, determining the levels of gene expression, and many...
Published: 7/25/2024   |   Inventor(s): Vincent Hill, Brian Holloway, Jothikumar Narayanan
Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC4XXX, AC5XXX, AC6XXX, Acid, ACXXXX, AE1BXX, AG1XXX, amplification, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, ELECTRON, Nucleic, OID-NCEZID-DFWED, PET, PHOTOINDUCED, PRIMER, TRANSFER, VAXXXX, VBXXXX, VCXXXX, VDXXXX, VEXXXX, VGXXXX, VHXXXX, VIXXXX, VJXXXX, VKXXXX, VLXXXX, VMXXXX, VNXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WHXXXX, WIXXXX, WMXXXX, XBXXXX, XCXXXX, XEXXXX, XHXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, ResearchProducts > Research Equipment, Application > Diagnostics, Application > Occupational Safety and Health, Application > Research Materials, TherapeuticArea > Oncology, ResearchProducts > Computational models/software, TherapeuticArea > Neurology, TherapeuticArea > Cardiology, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Psychiatry/Mental Health, TherapeuticArea > Immunology, Application > Software / Apps, Application > Vaccines, TherapeuticArea > Infectious Disease, TherapeuticArea > Geriatrics
Method for Finding Usable Portion of Sigmoid Curve (the Taylor Method), Improved Assay Readouts, and Enhanced Quality Control/Assurance
CDC researchers have developed algorithmic methods for determining sigmoid curve optimums and calculating component concentrations. Sigmoid curves are commonly generated in bioassays and used to calculate results. Various techniques have been used to define the curve, analyze the observations, and calculate a concentration. This technology is an...
Published: 7/25/2024   |   Inventor(s): Thomas Taylor
Keywords(s): AA2XXX, AA5XXX, AA6XXX, AAXXXX, AB4XXX, AC2XXX, AC4XXX, AC6XXX, ACXXXX, AD3XXX, ADXXXX, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, CURVE, Finding, OID-NCIRD-DBD, Portion, Sigmoid, USABLE, VBXXXX, VPXXXX, WAXXXX, WHXXXX, WIXXXX, WMXXXX, XHXXXX, XJXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Ophthalmology, TherapeuticArea > Cardiology, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Consumer Products, TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology, ResearchProducts > Computational models/software, Application > Software / Apps, Application > Diagnostics, ResearchProducts > Research Equipment, Application > Research Materials
Rapid and Sensitive Detection of Nucleic Acid Sequence Variations
The ability to easily detect small mutations in nucleic acids, such as single base substitutions, can provide a powerful tool for use in cancer detection, perinatal screens for inherited diseases, and analysis of genetic polymorphisms such as genetic mapping or for identification purposes. Current approaches make use of the mismatch that occurs between...
Published: 4/8/2024   |   Inventor(s): Kenji Adzuma, Kiyoshi Mizuuchi, Katsuhiko Yanagihara
Keywords(s): (4)r syndrome, AC6XXX, ACXXXX, AXXXXX, C syndrome, CA1AXX, CA1XXX, CAXXXX, Chromosome 4 ring syndrome, Chromosome 6 ring syndrome, Chromosome 7 ring syndrome, CXXXXX, Cystic fibrosis, Detection, DNA, Fragile X syndrome, G syndrome, Genetic, Huntington disease, Huntington disease; Huntington's disease, Hypertelorism with esophageal abnormality and hypospadias, IA6XXX, IAXXXX, Insertion, IXXXXX, Method, Mismatch-Targeted, Muscular dystrophy, Mutations, N syndrome, R(6) syndrome, R(7) syndrome, Syndrome X, Transposon, W syndrome, W syndrome; Syndrome W
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Oncology
Serotonin-Deficient Knock-out Mouse
Serotonin is an important modulator of many developmental, behavioral, and physiological processes, and it has been implicated in depression, anxiety, schizophrenia, obsessive compulsive disorders, and substance abuse. Serotonin’s pharmacology is extremely complex and it is mediated by seven of serotonin receptor subtypes and it is present in several...
Published: 7/25/2024   |   Inventor(s): Dennis Murphy
Keywords(s): AC6XXX, ACXXXX, AXXXXX, KNOCK-OUT, Mouse, MXXXXX, NC4XXX, NCXXXX, NXXXXX, Serotonin-Deficient, VEXXXX, WIXXXX
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Consumer Products, TherapeuticArea > Neurology, Application > Diagnostics, Application > Research Materials
Monoclonal Antibodies to HIV-1 Vpr
Available for licensing are monoclonal antibodies against HIV-1 viral protein R (Vpr) and the respective hybridoma cell lines expressing the same. The antibodies provide a means for detecting HIV-1 Vpr. Currently, the mechanism of HIV pathogenesis believed to involve viral replication inside immune cells and other cells. At present, there are no...
Published: 7/25/2024   |   Inventor(s): Ulrich Schubert, Terrence Phillips, Jonathan (Jon) Yewdell, Jeffrey Kopp
Keywords(s): (4)r syndrome, Abdominal obesity metabolic syndrome, AC6XXX, ACCESSORY, ACXXXX, Antibody-based, AXXXXX, Biological, C syndrome, Chromosome 4 ring syndrome, Chromosome 6 ring syndrome, Chromosome 7 ring syndrome, DA4AXX, DA4XXX, DAXXXX, DB4AXX, DB4XXX, DBXXXX, DC5AXX, DC5XXX, DCXXXX, DDXXXX, Detection, DXXXXX, G syndrome, HIV-1, Hypertelorism with esophageal abnormality and hypospadias, Metabolic syndrome X, Methodologies, monoclonal, N syndrome, Protein, QUANTIFICATION, R(6) syndrome, R(7) syndrome, SAMPLES, Syndrome X, VPR, W syndrome, W syndrome; Syndrome W
Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Vaccines, TherapeuticArea > Infectious Disease, Application > Therapeutics, Application > Diagnostics
Stem Cell Culture, Monitoring and Storage System
Available for licensing is a closed chamber that provides an environment for long-term culture of stem cells, stems cells of central nervous system (CNS) origin, embryonic stem cells, and other cells. The chamber is designed with top and bottom mounted cover slips that permit the observation of cells in culture under an optical microscope. This chamber...
Published: 4/8/2024   |   Inventor(s): Rea Ravin, James Sullivan, Ronald McKay
Keywords(s): AC1XXX, AC3XXX, AC6XXX, ACXXXX, AXXXXX
Category(s): Collaboration Sought > Licensing
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