Search Results - brian+holloway

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Photoinduced Electron Transfer Fluorescent Primer for Nucleic Acid Amplification

CDC scientists have developed a rapid and cost-efficient method for generating fluorescently labeled primers for PCR and real-time PCR. At present, fluorescent primers are useful for detecting and identifying microbes and specific nucleic acid sequences, amplifying nucleic acids for pyro-sequencing, determining the levels of gene expression, and many...

Published: 7/25/2024 | Inventor(s): Vincent Hill, Brian Holloway, Jothikumar Narayanan

Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC4XXX, AC5XXX, AC6XXX, Acid, ACXXXX, AE1BXX, AG1XXX, amplification, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, ELECTRON, Nucleic, OID-NCEZID-DFWED, PET, PHOTOINDUCED, PRIMER, TRANSFER, VAXXXX, VBXXXX, VCXXXX, VDXXXX, VEXXXX, VGXXXX, VHXXXX, VIXXXX, VJXXXX, VKXXXX, VLXXXX, VMXXXX, VNXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WHXXXX, WIXXXX, WMXXXX, XBXXXX, XCXXXX, XEXXXX, XHXXXX, YBXXXX

Detection and Differentiation of Pathogenic Fungi in Clinical Samples Using a Multi-Analyte Profiling System

This invention provides a rapid, sensitive and specific diagnostic tool for the detection of pathogenic fungi and subsequent species-specific discrimination. CDC scientists have developed nucleic acid probes to identify the six most medically important Candida species and endemic mycoses, and to differentiate them from other medically important fungi...

Published: 7/25/2024 | Inventor(s): Sanchita Das, Teresa Brown, Brian Holloway, Christine Morrison

Keywords(s): Bead, Beads, CANDIDA, CDC Docket Import, CDC Docket Import CDC Prosecuting, Clinical, Clinical SAMPLE, Compositions, DA1XXX, DAXXXX, Detection, Diagnose, Diagnosis, diagnostic, Diagnostic assay, Discriminate, discrimination, DXXXXX, FUNGAL, FUNGI, fungus, Methods, microarray, Nucleic, nucleic acid, OID-NCEZID-DFWED, PATHOGEN, PATHOGENIC, Probe, Species, VKXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, XEXXXX, XHXXXX, YAXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Occupational Safety and Health, Application > Diagnostics, Application > Therapeutics, Application > Consumer Products, TherapeuticArea > Infectious Disease, ResearchProducts > Research Equipment

Nucleic Acid-based Compositions and Methods for the Detection of Pathogenic Candida or Aspergillus Fungi Species

This invention pertains to the development of oligonucleotides for the rapid nucleic acid-based identification of Candida or Aspergillus fungi species in biological samples. This identification is accomplished by the targeting the internally transcribed spacer-2 (ITS2) region that are unique to various Candida species. The assay is sensitive, specific...

Published: 7/25/2024 | Inventor(s): Errol Reiss, Brian Holloway, Jong Shin, Christine Morrison

Keywords(s): AIDS, Aspergilli, Aspergillus, assay, CANDIDA, CANDIDA ALBICANS, candidiasis, CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, DA1XXX, DAXXXX, Detection, diagnostic, DXXXXX, FUNGAL, FUNGI, FUNGI COMPONENTS, fungus, HIV, Immuno-comprimised, IMMUNOCOMPROMISED, Methods, Spp, thrush, VKXXXX, VOXXXX, VPXXXX, WBXXXX, WCXXXX, WIXXXX, XCXXXX, XEXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Ophthalmology, TherapeuticArea > Cardiology, Application > Occupational Safety and Health, Application > Therapeutics, TherapeuticArea > Infectious Disease, TherapeuticArea > Dental, Application > Consumer Products, TherapeuticArea > Oncology, TherapeuticArea > Endocrinology

Real-Time PCR for Detecting Legionella Species and Discriminating Legionella pneumophila

Legionella pneumophila is the causative species in most cases of Legionnaires' disease (LD). CDC scientists have developed a real-time PCR assay capable of detecting all Legionella species and discriminating L. pneumophila from other Legionella species. LD is typically difficult to diagnose from a clinical standpoint as it confers no unique clinical...

Published: 7/25/2024 | Inventor(s): Brian Holloway, Karen McCaustland, Patrick Yang, Robert Benson

Keywords(s): DA3XXX, DAXXXX, Detection, DXXXXX, L., LEGIONELLA, Multiplexed, PCR, Pneumophilia, REAL-TIME, Spp

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Diagnostics