Nucleic Acid-based Compositions and Methods for the Detection of Pathogenic Candida or Aspergillus Fungi Species

Description:
This invention pertains to the development of oligonucleotides for the rapid nucleic acid-based identification of Candida or Aspergillus fungi species in biological samples. This identification is accomplished by the targeting the internally transcribed spacer-2 (ITS2) region that are unique to various Candida species. The assay is sensitive, specific and rapid. Implementation of the technology will facilitate earlier specific diagnoses, and lead to better antifungal therapy implementation for infected patients.
Patent Information:
For Information, Contact:
Jeremiah Mitzelfelt
NIH Technology Transfer
301-443-8518
jeremiah.mitzelfelt@nih.gov
Inventors:
Errol Reiss
Brian Holloway
Jong Shin
Christine Morrison
Keywords:
AIDS
Aspergilli
Aspergillus
assay
CANDIDA
CANDIDA ALBICANS
candidiasis
CDC Docket Import
CDC Docket Import CDC Prosecuting
Compositions
DA1XXX
DAXXXX
Detection
diagnostic
DXXXXX
FUNGAL
FUNGI
FUNGI COMPONENTS
fungus
HIV
Immuno-comprimised
IMMUNOCOMPROMISED
Methods
Spp
thrush
VKXXXX
VOXXXX
VPXXXX
WBXXXX
WCXXXX
WIXXXX
XCXXXX
XEXXXX
YBXXXX
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