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Real-time PCR Assay for Detection of Pneumococcal DNA and Diagnosis of Pneumococcal Disease

CDC scientists have developed a real-time PCR assay for diagnosing pneumococcal disease using amplification of the bacterial gene encoding pneumococcal surface adhesin A (PsaA). Pneumococcal isolation and identification is often complicated by 1) antimicrobial suppression of growth in culture and 2) contamination by normal flora alpha-streptococci....

Published: 7/25/2024 | Inventor(s): Edwin Ades, George Carlone, Karen McCaustland, Maria Da Gloria Carvalho, Jacquelyn Sampson

Keywords(s): assay, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, Detection, Development, Diagnosis, Disease, DNA, DXXXXX, PCR, PNEUMOCOCCAL, REAL-TIME

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Diagnostics

Real-Time PCR for Detecting Legionella Species and Discriminating Legionella pneumophila

Legionella pneumophila is the causative species in most cases of Legionnaires' disease (LD). CDC scientists have developed a real-time PCR assay capable of detecting all Legionella species and discriminating L. pneumophila from other Legionella species. LD is typically difficult to diagnose from a clinical standpoint as it confers no unique clinical...

Published: 7/25/2024 | Inventor(s): Brian Holloway, Karen McCaustland, Patrick Yang, Robert Benson

Keywords(s): DA3XXX, DAXXXX, Detection, DXXXXX, L., LEGIONELLA, Multiplexed, PCR, Pneumophilia, REAL-TIME, Spp

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Diagnostics