Search Results - huntington+disease

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Rapid and Sensitive Detection of Nucleic Acid Sequence Variations

The ability to easily detect small mutations in nucleic acids, such as single base substitutions, can provide a powerful tool for use in cancer detection, perinatal screens for inherited diseases, and analysis of genetic polymorphisms such as genetic mapping or for identification purposes. Current approaches make use of the mismatch that occurs between...

Published: 4/8/2024 | Inventor(s): Kenji Adzuma, Kiyoshi Mizuuchi, Katsuhiko Yanagihara

Keywords(s): (4)r syndrome, AC6XXX, ACXXXX, AXXXXX, C syndrome, CA1AXX, CA1XXX, CAXXXX, Chromosome 4 ring syndrome, Chromosome 6 ring syndrome, Chromosome 7 ring syndrome, CXXXXX, Cystic fibrosis, Detection, DNA, Fragile X syndrome, G syndrome, Genetic, Huntington disease, Huntington disease; Huntington's disease, Hypertelorism with esophageal abnormality and hypospadias, IA6XXX, IAXXXX, Insertion, IXXXXX, Method, Mismatch-Targeted, Muscular dystrophy, Mutations, N syndrome, R(6) syndrome, R(7) syndrome, Syndrome X, Transposon, W syndrome, W syndrome; Syndrome W

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Oncology

Receptor-Mediated Uptake of an Extracellular Bcl-X_L Fusion Protein Inhibits Apoptosis

The present invention relates to the field of apoptosis, in particular, it relates to apoptosis-modifying fusion proteins with at least two domains, one of which targets the fusion proteins to a target cell, and another of which modifies an apoptotic response of the target cell. For example, fusing various cell-binding domains to Bcl-XL and Bad allows...

Published: 4/8/2024 | Inventor(s): Richard Youle

Keywords(s): Adult spinal muscular atrophy, Alzheimer disease 1, Alzheimer disease 3, Alzheimer disease 4, Alzheimer disease type 1, Alzheimer disease type 4, Alzheimer disease, familial, type 3, CB1XXX, CBXXXX, CXXXXX, Huntington disease, Huntington disease; Huntington's disease, Spinal muscular atrophy, Spinal Muscular Atrophy 1, Spinal muscular atrophy 4, Werdnig-Hoffmann disease

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology, TherapeuticArea > Immunology