Search Results - quantification

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Novel Magnetic Resonance Spectroscopy (MRS) Technique to Quantify Brain Metabolites

With respect to quantification of metabolites in the brain, conventional methods of magnetic resonance spectroscopy (MRS) yield results that are highly variable and highly dependent on the sequence type being applied. This invention describes a novel MRS technique that involves preparing longitudinal steady states at different flip angles using trains...

Published: 7/25/2024 | Inventor(s): Jun Shen, Linqing Li

Keywords(s): AAXXXX, DRIVEN, IMAGING, ImagingMRI, LINEAR, METABOLITE, MRI, NCXXXX, Probing, QUANTIFICATION, Relaxation, RF, States, Steady, VCXXXX, VEXXXX, Vivo, VNXXXX, WBXXXX, XFXXXX, YAXXXX, YDXXXX

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Neurology, TherapeuticArea > Psychiatry/Mental Health, Application > Non-Medical Devices, TherapeuticArea > Oncology, Application > Software / Apps, Application > Medical Devices, Application > Diagnostics, Application > Research Materials

Improved Protein Quantification Process and Vaccine Quality Control Production

This CDC invention is a method for identifying and quantifying a group of proteins in a complex mixture by a liquid chromatography-tandem mass spectrometry assay. The technology was developed for influenza although it can be used for a wide variety of protein quantification applications. As specifically developed, conserved peptides from the proteins...

Published: 7/25/2024 | Inventor(s): James Pirkle, Ruben Donis, Leah Luna, Zhu Guo, John Barr, Tracie Williams

Keywords(s): AA2XXX, AA5XXX, AA6XXX, AG2XXX, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, CONTROL, DA4BXX, DA4XXX, DAXXXX, DDXXXX, DXXXXX, Improved, PROCESS, Protein, Quality, QUANTIFICATION, Therewith, Vaccine, viral, VJXXXX, VKXXXX, VLXXXX, WBXXXX, WFXXXX, WHXXXX, WIXXXX, WMXXXX, XCXXXX, XHXXXX, YAXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Consumer Products, Application > Research Materials, Application > Diagnostics, ResearchProducts > Research Equipment, Application > Occupational Safety and Health

Improved Standard for Immune System Recovery Assay

Monitoring an immune system that has been depleted by infection (e.g., HIV), chemotherapy, or progenitor cell transplantation is vital to assessing individual’s recovery status. This technology provides a new plasmid standard to be used as part of the existing TREC assay. This new plasmid has a shorter insert than the commercially available one, which...

Published: 7/25/2024 | Inventor(s): Richard Koup, Brenna Hill, Daniel Douek

Keywords(s): Cell, Circles, DAXXXX, DDXXXX, DXXXXX, EXCISION, Humans, MEASURE, OUTPUT, PLASMID, QUANTIFICATION, rearrangement, RECEPTOR, RM, T, THYMIC, TREC, WIXXXX

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, TherapeuticArea > Infectious Disease

Monoclonal Antibodies to HIV-1 Vpr

Available for licensing are monoclonal antibodies against HIV-1 viral protein R (Vpr) and the respective hybridoma cell lines expressing the same. The antibodies provide a means for detecting HIV-1 Vpr. Currently, the mechanism of HIV pathogenesis believed to involve viral replication inside immune cells and other cells. At present, there are no...

Published: 7/25/2024 | Inventor(s): Ulrich Schubert, Terrence Phillips, Jonathan (Jon) Yewdell, Jeffrey Kopp

Keywords(s): (4)r syndrome, Abdominal obesity metabolic syndrome, AC6XXX, ACCESSORY, ACXXXX, Antibody-based, AXXXXX, Biological, C syndrome, Chromosome 4 ring syndrome, Chromosome 6 ring syndrome, Chromosome 7 ring syndrome, DA4AXX, DA4XXX, DAXXXX, DB4AXX, DB4XXX, DBXXXX, DC5AXX, DC5XXX, DCXXXX, DDXXXX, Detection, DXXXXX, G syndrome, HIV-1, Hypertelorism with esophageal abnormality and hypospadias, Metabolic syndrome X, Methodologies, monoclonal, N syndrome, Protein, QUANTIFICATION, R(6) syndrome, R(7) syndrome, SAMPLES, Syndrome X, VPR, W syndrome, W syndrome; Syndrome W

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Vaccines, TherapeuticArea > Infectious Disease, Application > Therapeutics, Application > Diagnostics

Software for Fully Automating Myocardial Perfusion Quantification

Software is has been developed and available for licensing that fully automates image processing for the quantification of myocardial blood flow (MBF) pixel maps from firstpass contrast-enhanced cardiac magnetic resonance (CMR) perfusion images. The system removes the need for laborious manual quantitative CMR perfusion pixel map processing and can...

Published: 7/29/2024 | Inventor(s): Andrew Arai, Matthew Jacobs, Mitchel Benovoy, Li-Yueh Hsu

Keywords(s): Automated, Cardiac, First-pass, FULLY, IMAGING, Magnetic, MYOCARDIAL, Perfusion, QUANTIFICATION, Resonance, System, VDXXXX, WIXXXX, XJXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials, ResearchProducts > Computational models/software, TherapeuticArea > Cardiology, Application > Software / Apps