Improved Standard for Immune System Recovery Assay

Description:
Monitoring an immune system that has been depleted by infection (e.g., HIV), chemotherapy, or progenitor cell transplantation is vital to assessing individual’s recovery status. This technology provides a new plasmid standard to be used as part of the existing TREC assay. This new plasmid has a shorter insert than the commercially available one, which means it now matches the PCR product generated in the qPCR reaction in the TREC assay. Additionally, the new plasmid is easier to grow up than the existing standard.
Patent Information:
For Information, Contact:
Carol Salata
Technology Development Manager
NIH Technology Transfer
240-627-3727
csalata@mail.nih.gov
Inventors:
Richard Koup
Brenna Hill
Daniel Douek
Keywords:
Cell
Circles
DAXXXX
DDXXXX
DXXXXX
EXCISION
Humans
MEASURE
OUTPUT
PLASMID
QUANTIFICATION
rearrangement
RECEPTOR
RM
T
THYMIC
TREC
WIXXXX
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