Search Results - humans

4 Results

Sort By:

DNA Methylation Based Non-invasive Blood Diagnostic Assay for Precision Cancer Detection and Classification

This technology includes a panel of 46 genomic loci of DNA methylation (represented by CpG dinucleotides on different chromosomes) with application in blood-based cancer screening. The markers robustly distinguish tumor from normal samples using 8 loci and classify 13 different tumor types. Using 39 loci, inventors were able to discriminate between...

Published: 7/25/2024 | Inventor(s): Gennady Margolin, Laura Elnitski

Keywords(s): assay, Based, Blood, CANCER, CLASSIFICATION, Detection, diagnostic, DNA, Humans, Methylation, NON-INVASIVE, PRECISION, VCXXXX, WBXXXX, WIXXXX, XEXXXX

Category(s): Application > Research Materials, Application > Diagnostics, TherapeuticArea > Oncology, Application > Therapeutics

Non-invasive Method for Ebola Virus Infection Detection in Great Apes and Other Wildlife Hosts

Ebola virus surveillance in wildlife vectors of infection transmission to humans.

Published: 7/25/2024 | Inventor(s): Nancy Sullivan

Keywords(s): ACXXXX, Apes, Detection, Ebola, HOSTS, HostsNon-invasive, Humans, Infection, Method, NON-INVASIVE, Nucleoprotien, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, primate, RM, Surveillance, TRANSMISSION, vectors, virus, VLXXXX, WIXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Research Materials

Improved Standard for Immune System Recovery Assay

Monitoring an immune system that has been depleted by infection (e.g., HIV), chemotherapy, or progenitor cell transplantation is vital to assessing individual’s recovery status. This technology provides a new plasmid standard to be used as part of the existing TREC assay. This new plasmid has a shorter insert than the commercially available one, which...

Published: 7/25/2024 | Inventor(s): Richard Koup, Brenna Hill, Daniel Douek

Keywords(s): Cell, Circles, DAXXXX, DDXXXX, DXXXXX, EXCISION, Humans, MEASURE, OUTPUT, PLASMID, QUANTIFICATION, rearrangement, RECEPTOR, RM, T, THYMIC, TREC, WIXXXX

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, TherapeuticArea > Infectious Disease

Moraxella Catarrhalis Lipooligosaccharide Based Conjugate Vaccines for the Prevention of Otitis Media and Respiratory Infections

Moraxella catarrhalis is one of the three leading causative agents of otitis media in children. This is due in part to the current immunizations of children with Streptococcus pneumoniae polysaccharide and conjugate vaccines to prevent otitis media. The proportion of otitis media caused by pneumococcal strains covered by the vaccines have decreased...

Published: 7/25/2024 | Inventor(s): John Robbins, Xin-xing Gu

Keywords(s): BBXXXX, BCXXXX, BRANHAMELLA, CATARHALIS, Catarrhalis, DC4XXX, DCXXXX, DETOXIFIED, DXXXXX, HAEMOPHILUS, Haemophilus influenzae, Humans, Immunization, INFECTIONS, INFLUENZAE, Intranasal, Lipooligosaccharide, LIPOOLIGOSACCHARIDE-BASED, MORAXELLA, NONTYPEABLE, OTITIS MEDIA, Patent Category - Biotechnology, Prevention, Tetanus, UAXXXX, Vaccine, With...

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Application > Vaccines, TherapeuticArea > Rare / Neglected Diseases