Search Results - gennady+margolin

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DNA Methylation Based Non-invasive Blood Diagnostic Assay for Precision Cancer Detection and Classification

This technology includes a panel of 46 genomic loci of DNA methylation (represented by CpG dinucleotides on different chromosomes) with application in blood-based cancer screening. The markers robustly distinguish tumor from normal samples using 8 loci and classify 13 different tumor types. Using 39 loci, inventors were able to discriminate between...

Published: 7/25/2024 | Inventor(s): Gennady Margolin, Laura Elnitski

Keywords(s): assay, Based, Blood, CANCER, CLASSIFICATION, Detection, diagnostic, DNA, Humans, Methylation, NON-INVASIVE, PRECISION, VCXXXX, WBXXXX, WIXXXX, XEXXXX

Category(s): Application > Research Materials, Application > Diagnostics, TherapeuticArea > Oncology, Application > Therapeutics

Non-invasive Pan-Cancer Detection Method

One of four deaths in the United States is due to cancer despite an emphasis on prevention, early detection, and treatment that has lowered cancer death rates by 20% in the past two decades. Further improvements in survival rates are likely to come from improving the limits of detection sensitivity at earlier stages of cancer. New approaches that rely...

Published: 7/25/2024 | Inventor(s): Gennady Margolin, Hanna Petrykowska, Laura Elnitski

Keywords(s): CAXXXX, Detection, Listed LPM Campbell as of 4/17/2015, Methods, Pan-Cancer, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, VCXXXX, WBXXXX, XBXXXX, XCXXXX, XEXXXX, YAXXXX, YBXXXX, YGXXXX

Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, Application > Diagnostics, Application > Research Materials, ResearchProducts > Computational models/software, TherapeuticArea > Oncology, Application > Software / Apps