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Anti-Nucleoprotein Crimean-Congo Hemorrhagic Fever Virus Monoclonal Antibodies for Assay Creation
Crimean-Congo hemorrhagic fever (CCHF) is the most widespread form of viral hemorrhagic fever, found in Eastern and Southern Europe, the Mediterranean, northwestern China, central Asia, Africa, the Middle East, and the Indian subcontinent. Typically beginning with non-specific fever, myalgia, nausea, diarrhea, and general malaise, symptoms of infection...
Published: 7/3/2025
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Inventor(s):
Daniel Douek
,
David Hawman
,
Leonid Serebryannyy
,
Noemia Santana Lima
,
Chaim Schramm
,
Sarah Smith (Kerscher)
,
Amy Henry
,
Alicen Spaulding
Keywords(s):
Category(s):
Application
,
Application > Diagnostics
,
Collaboration Sought
,
Collaboration Sought > Licensing
,
Collaboration Sought > Materials Available
,
ResearchProducts > Antibodies
,
TherapeuticArea
,
TherapeuticArea > Infectious Disease
,
TherapeuticArea > Immunology
,
TherapeuticArea > Rare/Neglected Diseases
Improved Standard for Immune System Recovery Assay
Monitoring an immune system that has been depleted by infection (e.g., HIV), chemotherapy, or progenitor cell transplantation is vital to assessing individual’s recovery status. This technology provides a new plasmid standard to be used as part of the existing TREC assay. This new plasmid has a shorter insert than the commercially available one, which...
Published: 10/28/2024
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Inventor(s):
Richard Koup
,
Brenna Hill
,
Daniel Douek
Keywords(s):
Cell
,
Circles
,
DAXXXX
,
DDXXXX
,
DXXXXX
,
EXCISION
,
Humans
,
MEASURE
,
OUTPUT
,
PLASMID
,
QUANTIFICATION
,
rearrangement
,
RECEPTOR
,
RM
,
T
,
THYMIC
,
TREC
,
WIXXXX
Category(s):
Collaboration Sought > Licensing
,
Application > Diagnostics
,
Application > Research Materials
,
TherapeuticArea > Infectious Disease
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