
HOME		SEARCH		RSS FEED		SUBSCRIBE

Search Results - ydxxxx

13 Results

Sort By:

Novel Inactivated Zika Vaccine Candidate Based on Purified Wild-type Zika Virus — for Zika Vaccine and Diagnostic Assay Development

Zika virus (ZIKV) spreads to people primarily through bite by infected Aedes mosquitoes. ZIKV infection during pregnancy can cause stillbirths or affect the fetus by causing serious birth defects, such as microcephaly and other brain defects. Although uncommon, adults with ZIKV can also develop Guillain-Barre syndrome and other neurological disorders....

Published: 4/8/2024 | Inventor(s): Holli Giebler, Windy Baldwin, Claire Kinney, Jill Livengood

Keywords(s): Compositions, Immunogenic, Methods, SAME, vaccines, YBXXXX, YCXXXX, YDXXXX, YXXXXX, Zika

Category(s):

Multiplexing Homocysteine in Primary Newborn Screening Assays Using Maleimides as Select Derivatization Agents

Homocystinuria (HCU), a group of inherited disorders, causes symptoms ranging from failure to thrive and developmental delays in infants or young children to abnormal blood clots with onset in adults.1 Approximately 1 in 200,000 to 335,000 people have HCU globally.2 Various clinical settings use the dried blood spot (DBS) for sample collection methods...

Published: 7/25/2024 | Inventor(s): Charles Pickens, Konstantinos Petritis

Keywords(s): 4AXXXX, Agents, ASSAYS, Derivatization, Hcy, HOMOCYSTEINE, Maleimides, Multiplexing, Newborn, Primary, screening, SELECTIVE, VDXXXX, VPXXXX, WFXXXX, WHXXXX, WIXXXX, XCXXXX, XHXXXX, YAXXXX, YDXXXX, YFXXXX

Category(s): TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology, TherapeuticArea > Endocrinology, TherapeuticArea > Ophthalmology, Application > Consumer Products, TherapeuticArea > Dental, Application > Research Materials, ResearchProducts > Research Equipment, Application > Occupational Safety and Health, Application > Diagnostics

Novel Magnetic Resonance Spectroscopy (MRS) Technique to Quantify Brain Metabolites

With respect to quantification of metabolites in the brain, conventional methods of magnetic resonance spectroscopy (MRS) yield results that are highly variable and highly dependent on the sequence type being applied. This invention describes a novel MRS technique that involves preparing longitudinal steady states at different flip angles using trains...

Published: 7/25/2024 | Inventor(s): Jun Shen, Linqing Li

Keywords(s): AAXXXX, DRIVEN, IMAGING, ImagingMRI, LINEAR, METABOLITE, MRI, NCXXXX, Probing, QUANTIFICATION, Relaxation, RF, States, Steady, VCXXXX, VEXXXX, Vivo, VNXXXX, WBXXXX, XFXXXX, YAXXXX, YDXXXX

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Neurology, TherapeuticArea > Psychiatry/Mental Health, Application > Non-Medical Devices, TherapeuticArea > Oncology, Application > Software / Apps, Application > Medical Devices, Application > Diagnostics, Application > Research Materials

Real-Time RT-PCR Detection of Rickettsia species -- PanR6/Total Nucleic Acid Assay with High Sensitivity and Specificity

Rickettsial infections are caused by bacteria from the Rickettsia genus which are often spread by biting ticks, fleas, mites or lice. Rickettsia can cause mild to severe illness and Rickettsia species can be found worldwide. Early stage, nonspecific symptoms of infections can make clinical diagnosis difficult. Rickettsial infection symptoms, if present,...

Published: 7/25/2024 | Inventor(s): Ida Chung, Cecilia Kato

Keywords(s): Acid, Detection, Genus, NCEZID-DVBD, Nucleic, Rickettsia, TOTAL, VJXXXX, WBXXXX, WFXXXX, WHXXXX, WIXXXX, WMXXXX, XDXXXX, XEXXXX, YBXXXX, YDXXXX

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Research Materials, Application > Non-Medical Devices, Application > Occupational Safety and Health, Application > Therapeutics, TherapeuticArea > Infectious Disease, Application > Diagnostics, Application > Consumer Products, Application > Medical Devices

Personalized Cancer Evaluation (PERCEVAL) Method and Software

Cancer represents the leading cause of morbidity and mortality worldwide, with approximately 14 million new cases and 8.2 million cancer related deaths in 2012. This number is predicted to rise by approximately 70% over the next two decades according to the World Health Organization. Prognosis depends heavily on both early detection and frequent monitoring...

Published: 7/25/2024 | Inventor(s): David Campo

Keywords(s): CANCER, EVALUATION, NCHHSTP, NCHHSTP-DVH, PERCEVAL, Personalized, WBXXXX, XBXXXX, YDXXXX

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, ResearchProducts > Computational models/software, Application > Software / Apps, Application > Diagnostics

Monoclonal Antibodies for Specific Detection of Dengue Virus Sub-type 4 in Human Serum

Dengue Virus (DENV) non-structural protein 1 (NS1) is secreted in blood during the acute phase of viremic DENV infection. While there are commercially available ELISA assays for DENV NS1 detection, these tests have limited sensitivity (50-70%), do not determine the serotype of the infecting DENV, do not detect all four serotypes equally, or are less...

Published: 7/25/2024 | Inventor(s): Tesfaye Taye, Elizabeth Hunsperger

Keywords(s): 1, 4, antibodies, DENGUE, DENV, monoclonal, NCEZID, NCEZID-DVBD, Non-structural, NS1, Protein, Serotype, Specific, virus, VLXXXX, WBXXXX, WHXXXX, WIXXXX, XAXXXX, XEXXXX, YBXXXX, YDXXXX

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics, TherapeuticArea > Immunology, Application > Research Materials, ResearchProducts > Antibodies, Application > Diagnostics

Rapid Colorimetric Detection of Zika Virus from Serum and Urine Specimens by RT-LAMP (Reverse Transcription Loop-Mediated Isothermal Amplification).

The Zika virus (ZIKV) can be passed from a pregnant woman to her fetus. Resulting infection by this virus can cause early miscarriage and a pattern of severe birth defects in fetuses and infants. Therefore, a rapid diagnostic assay that can be performed throughout pregnancy in a clinical setting is vital for prenatal care of women living in areas where...

Published: 7/25/2024 | Inventor(s): Amanda Calvert

Keywords(s): amplification, COLORIMETRIC, Detection, Isothermal, Loop-, Mediated, NCEZID-DVBD, RAPID, Reverse, RT-LAMP, RT-LAMP., SERUM, SPECIMENS, transcription, Urine, virus, VLXXXX, WBXXXX, WFXXXX, WHXXXX, WIXXXX, XEXXXX, YBXXXX, YDXXXX, YFXXXX, Zika

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Consumer Products, Application > Diagnostics, Application > Therapeutics, Application > Research Materials, Application > Occupational Safety and Health

Real-time RT-PCR assay for Detection of Live Attenuated Influenza Vaccine for A and B Viruses

Upon intranasal vaccination, live attenuated influenza vaccine (LAIV) viruses may replicate within the nose for several days. Current clinical diagnostic tests cannot distinguish between LAIV viruses and multiple influenza viruses in recently inoculated patients that present with respiratory symptoms. This poses a problem for the diagnosis and treatment...

Published: 7/25/2024 | Inventor(s): Stephen Lindstrom, Kai-Hui Wu, LaShondra Berman, Christine Warnes, Bo Shu

Keywords(s): assay, Assays., Attenuated, CDC Docket Import, CDC Docket Import CDC Prosecuting, CDCRM, DA4XXX, Detection, Human, Including, INFLUENZA, LAIV, LAIV-A, LAIV-B, Listed LPM Surabian as of 4/15/2015, Live, NCIRD-ID, PCR, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, REAL-TIME, respiratory, RT-PCR, SPECIMENS, States., United, Vaccine, Viruses, VLXXXX, WBXXXX, WIXXXX, XEXXXX, XHXXXX, YDXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics, Application > Diagnostics, Application > Research Materials, ResearchProducts > Research Equipment

Inhibition of HIV Infection through Chemoprophylaxis Using Emtricitabine and Tenofovir

The invention is directed to prophylactic administration of emtricitabine (FTC) in combination with tenofovir or its prodrug, tenofovir disoproxil fumarate (TDF), to protect against transmission of human immunodeficiency virus (HIV) infection. Also disclosed are other nucleoside reverse transcriptase inhibitors (NRTIs) and nucleotide reverse transcriptase...

Published: 7/25/2024 | Inventor(s): Thomas Folks, Robert Janssen, Ronald Otten, Jose Garcia Lerma, Walid Heneine

Keywords(s): CDC Docket Import, CDC Docket Import CDC Prosecuting, Chemoprophylaxis, HIV, Infection, inhibition, OID-NCHHSTP-DHPSE, VLXXXX, WMXXXX, YCXXXX, YDXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Consumer Products

Diagnostic Antigens for the Identification of Latent Tuberculosis Infection

CDC researchers have developed technology for sero-diagnosis of typically symptomless latent stage tuberculosis disease, posing a threat to individuals under immunosuppressive or anti-inflammatory therapies. Specifically, this diagnostic approach exploits M. tuberculosis secreted latency specific antigens, such as alpha-crystallin, in the blood or urine...

Published: 7/25/2024 | Inventor(s): Manon Deslauriers, Kristin Birkness, Peter King, Bernard Beall, Frederick Quinn

Keywords(s): ANTIGENS, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, DC4XXX, DCXXXX, DDXXXX, DEXXXX, diagnostic, DXXXXX, Granuloma, Human, IA3XXX, Identification, Latent, Methods, Model, OID-NCHHSTP-DTE, TUBERCULOSIS, VAXXXX, Vitro, VJXXXX, WBXXXX, WFXXXX, WIXXXX, XAXXXX, XCXXXX, YBXXXX, YDXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Geriatrics, TherapeuticArea > Immunology, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Research Materials, Application > Diagnostics, ResearchProducts > Antibodies, Application > Vaccines, Application > Occupational Safety and Health

1 2

|

|

|

© 2024. All Rights Reserved. Powered by Inteum