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Rapid Colorimetric Detection of Zika Virus from Serum and Urine Specimens by RT-LAMP (Reverse Transcription Loop-Mediated Isothermal Amplification).

The Zika virus (ZIKV) can be passed from a pregnant woman to her fetus. Resulting infection by this virus can cause early miscarriage and a pattern of severe birth defects in fetuses and infants. Therefore, a rapid diagnostic assay that can be performed throughout pregnancy in a clinical setting is vital for prenatal care of women living in areas where...

Published: 7/25/2024 | Inventor(s): Amanda Calvert

Keywords(s): amplification, COLORIMETRIC, Detection, Isothermal, Loop-, Mediated, NCEZID-DVBD, RAPID, Reverse, RT-LAMP, RT-LAMP., SERUM, SPECIMENS, transcription, Urine, virus, VLXXXX, WBXXXX, WFXXXX, WHXXXX, WIXXXX, XEXXXX, YBXXXX, YDXXXX, YFXXXX, Zika

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Consumer Products, Application > Diagnostics, Application > Therapeutics, Application > Research Materials, Application > Occupational Safety and Health

On-site in vitro Diagnostic: Real-time Loop-Mediated Isothermal Amplification Detection of HIV-2 Groups A and B

This CDC-developed technology entails a nucleic acid-based HIV-2 in vitro diagnostic assay that is well-suited for use in mobile testing units/vehicles or resource-limited settings, for example, many areas of West Africa. Because HIV-2 requires unique treatment regimens, accurate, early diagnosis is crucial for effective care and directing treatment....

Published: 7/25/2024 | Inventor(s): Sherry Owen, Donna Rudolph, Timothy Granade, Ae Saekhou Youngpairoj, Chou-Pong Pau, Kelly Curtis, Philip Niedzwiedz

Keywords(s): AIDS, amplification, B, DA4AXX, DA4XXX, DAXXXX, Detection, diagnostic, Diagnostic assay, diagnostic in vitro, Diagnostic System, DXXXXX, Field-usable, GCXXXX, Groups, HIV-2, Isothermal, LAMP, Loop-Mediated, LOW INPUT, OID-NCHHSTP-DHPSE, Reverse-Transcription, RT-LAMP, VLXXXX, WBXXXX, WFXXXX, WIXXXX, WMXXXX, XEXXXX, YBXXXX, YEXXXX

Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, Application > Research Materials, Application > Diagnostics, Application > Therapeutics, Application > Consumer Products, TherapeuticArea > Infectious Disease

Simple and Rapid Assay to Detect Acute Subtype B and Group M HIV-1 Infections

Within recent years, point-of-care (POC) testing has allowed for many individuals to be screened for and provided with HIV test results. It is critical to be able to accurately detect acute HIV infections as this is a stage where the risk of transmission is great. Additionally, early HIV detection could lead to less high-risk behavior, thereby reducing...

Published: 7/25/2024 | Inventor(s): Sherry Owen, Donna Rudolph, Kelly Curtis, Philip Niedzwiedz

Keywords(s): AA2XXX, AA5XXX, AAXXXX, AC1XXX, AC3XXX, AC4XXX, ACXXXX, AIDS, amplification, AXXXXX, B, CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, DA4AXX, DA4XXX, DAXXXX, Detection, diagnostic, DXXXXX, Field, Field-diagnostic, Field-usable, GROUP, HIV, HIV-1, HIV-2, IN-SITU, Isothermal, LAMP, LIMITED-RESOURCE, Listed LPM Houze as of 4/15/2015, Loop-Mediated, LOW INPUT, M, Methods, NCHHSTP, OID-NCHHSTP-DHPSE, On-demand, PCR, PCR ALTERNATIVE, Portable, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, RAPID, Reverse-Transcription, RT-LAMP, Subtype, viral, VIRAL DIAGNOSTIC, virus, VLXXXX, WBXXXX, WIXXXX, XCXXXX, XEXXXX, XHXXXX, YAXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Infectious Disease, ResearchProducts > Research Equipment