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Monoclonal Antibodies to the HIV-1 Core Protein p24

The core proteins of HIV-1 are secreted into the environment during replication in the human body. The detection of the core protein p24 (molecular mass of 24 kilodaltons) serves as an indicator of early HIV-1 infection, and assays detecting it have been available since the late 1980s. However, the development of a rapid assay for the detection of HIV-1...

Published: 7/25/2024 | Inventor(s): Chou-Pong Pau, Shon Nguyen, Susan Wells, Sherry Owen, Jason Goldstein, Dennis Bagarozzi, Timothy Granade

Keywords(s): antibodies, Core, DA4XXX, DDXXXX, HIV-1, Listed LPM Houze as of 4/15/2015, monoclonal, NCHHSTP-DHAP, P24, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Protein, VLXXXX, WBXXXX, WIXXXX, XAXXXX, XHXXXX, YBXXXX, YFXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, TherapeuticArea > Immunology, ResearchProducts > Antibodies, Application > Diagnostics, Application > Research Materials, ResearchProducts > Research Equipment

On-site in vitro Diagnostic: Real-time Loop-Mediated Isothermal Amplification Detection of HIV-2 Groups A and B

This CDC-developed technology entails a nucleic acid-based HIV-2 in vitro diagnostic assay that is well-suited for use in mobile testing units/vehicles or resource-limited settings, for example, many areas of West Africa. Because HIV-2 requires unique treatment regimens, accurate, early diagnosis is crucial for effective care and directing treatment....

Published: 7/25/2024 | Inventor(s): Sherry Owen, Donna Rudolph, Timothy Granade, Ae Saekhou Youngpairoj, Chou-Pong Pau, Kelly Curtis, Philip Niedzwiedz

Keywords(s): AIDS, amplification, B, DA4AXX, DA4XXX, DAXXXX, Detection, diagnostic, Diagnostic assay, diagnostic in vitro, Diagnostic System, DXXXXX, Field-usable, GCXXXX, Groups, HIV-2, Isothermal, LAMP, Loop-Mediated, LOW INPUT, OID-NCHHSTP-DHPSE, Reverse-Transcription, RT-LAMP, VLXXXX, WBXXXX, WFXXXX, WIXXXX, WMXXXX, XEXXXX, YBXXXX, YEXXXX

Category(s): Collaboration Sought > Licensing, Application > Occupational Safety and Health, Application > Research Materials, Application > Diagnostics, Application > Therapeutics, Application > Consumer Products, TherapeuticArea > Infectious Disease

A Device for Simultaneous and Rapid Diagnosis and Detection of Recent and Long Term HIV-1 Infection

CDC scientists have developed a device for simultaneous rapid diagnosis of HIV infection and for identification of recent HIV-1 infection. The device utilizes immunochromatographic or flow-through principles to detect HIV antibodies within clinical samples. This device may be used for diagnosis of HIV infection, as well as to distinguish between recent...

Published: 7/25/2024 | Inventor(s): Chou-Pong Pau, Steve McDougal, Timothy Granade

Keywords(s): assay, CDC Docket Import, CDC Docket Import CDC Prosecuting, Detection, Development, Diagnosis, diagnostic, HIV, HIV-1, Infection, LONG, RAPID, RECENT, TERM, VLXXXX, WBXXXX, WFXXXX, WIXXXX, WMXXXX, XAXXXX, XCXXXX, XDXXXX, XEXXXX, YAXXXX, YFXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Occupational Safety and Health, ResearchProducts > Antibodies, Application > Diagnostics, Application > Therapeutics, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Non-Medical Devices, TherapeuticArea > Immunology, Application > Medical Devices