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Real-time RT-PCR assay for Detection of Live Attenuated Influenza Vaccine for A and B Viruses
Case ID:
TAB-2937
Web Published:
12/6/2022
Description:
Upon intranasal vaccination, live attenuated influenza vaccine (LAIV) viruses may replicate within the nose for several days. Current clinical diagnostic tests cannot distinguish between LAIV viruses and multiple influenza viruses in recently inoculated patients that present with respiratory symptoms. This poses a problem for the diagnosis and treatment of patients with respiratory symptoms, as these symptoms may not be caused by influenza. CDC researchers have developed a real-time RT-PCR assay to detect the presence of LAIV viruses. This test is rapid, accurate, and provides diagnostic data about whether patient respiratory symptoms are due to wild-type influenza or LAIV viruses. Detection of LAIV viruses with this assay will allow practitioners to investigate other pathogens as causative agents for a patient's respiratory symptoms.
Patent Information:
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Serial No.
Patent No.
File Date
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Patent Status
Direct Link:
https://nih.technologypublisher.com/tech/Real-time_RT-PCR_assay_for_Detection _of_Live_Attenuated_Influenza_Vaccine_for_A_and_B_Viruses
Category(s):
Licensing
Infectious Disease
Therapeutics
Diagnostics
Research Materials
Research Equipment
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For Information, Contact:
Jonathan Motley
Fellow
NIH Technology Transfer
jonathan.motley@nih.gov
Inventors:
Stephen Lindstrom
Kai-Hui Wu
LaShondra Berman
Christine Warnes
Bo Shu
Keywords:
assay
Assays.
Attenuated
CDC Docket Import
CDC Docket Import CDC Prosecuting
CDCRM
DA4XXX
Detection
Human
Including
INFLUENZA
LAIV
LAIV-A
LAIV-B
Listed LPM Surabian as of 4/15/2015
Live
NCIRD-ID
PCR
Post LPM Assignment Set 20150420
Pre LPM working set 20150418
REAL-TIME
respiratory
RT-PCR
SPECIMENS
States.
United
Vaccine
Viruses
VLXXXX
WBXXXX
WIXXXX
XEXXXX
XHXXXX
YDXXXX
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