Search Results - bernard+beall

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Diagnostic Antigens for the Identification of Latent Tuberculosis Infection

CDC researchers have developed technology for sero-diagnosis of typically symptomless latent stage tuberculosis disease, posing a threat to individuals under immunosuppressive or anti-inflammatory therapies. Specifically, this diagnostic approach exploits M. tuberculosis secreted latency specific antigens, such as alpha-crystallin, in the blood or urine...

Published: 7/25/2024 | Inventor(s): Manon Deslauriers, Kristin Birkness, Peter King, Bernard Beall, Frederick Quinn

Keywords(s): ANTIGENS, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, DC4XXX, DCXXXX, DDXXXX, DEXXXX, diagnostic, DXXXXX, Granuloma, Human, IA3XXX, Identification, Latent, Methods, Model, OID-NCHHSTP-DTE, TUBERCULOSIS, VAXXXX, Vitro, VJXXXX, WBXXXX, WFXXXX, WIXXXX, XAXXXX, XCXXXX, YBXXXX, YDXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Geriatrics, TherapeuticArea > Immunology, Application > Consumer Products, TherapeuticArea > Infectious Disease, Application > Research Materials, Application > Diagnostics, ResearchProducts > Antibodies, Application > Vaccines, Application > Occupational Safety and Health

Novel In Vitro Granuloma Model for Studying Tuberculosis and Drug Efficacy

CDC researchers have developed an in vitro model system designed to simulate early-stage Mycobacterium tuberculosis infection and induced granuloma formation. This modeling platform can be used for studying tuberculosis pathogenicity, identifying phenotypically-interesting clinical isolates, studying early-stage host cytokine/chemokine responses, and...

Published: 7/25/2024 | Inventor(s): Manon Deslauriers, Kristin Birkness, Peter King, Bernard Beall, Frederick Quinn

Keywords(s): AC4XXX, AC5XXX, ACXXXX, ANTIGENS, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, DC4XXX, DCXXXX, DDXXXX, DEXXXX, diagnostic, DXXXXX, Granuloma, Human, IA3XXX, Identification, Latent, Methods, Model, OID-NCHHSTP-DTE, TUBERCULOSIS, Vitro, VJXXXX, WBXXXX, WFXXXX, WIXXXX, WMXXXX, XHXXXX, YBXXXX, YFXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Vaccines, Application > Consumer Products, Application > Occupational Safety and Health, ResearchProducts > Research Equipment, TherapeuticArea > Immunology, Application > Research Materials, Application > Diagnostics

Peptide Vaccines Against Group A Streptococci

This invention relates to synthetic immunoreactive peptides, which are portions of the M proteins of the most prevalent Group A Streptococcus (GAS) serotypes in the United States. These peptides may be useful in development of a flexible, multivalent GAS vaccine. They can be recognized by M type-specific antibodies and are capable of eliciting functional...

Published: 7/25/2024 | Inventor(s): George Carlone, Jacquelyn Sampson, Edwin Ades, Bernard Beall

Keywords(s): Against, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, DB3XXX, DBXXXX, DC4XXX, DCXXXX, GROUP, OID-NCIRD-DBD, Peptide, Streptococci, vaccines

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Infectious Disease